Evidence map›Paper›PMID 28043109›Full record

ArticleInternational neurourology journal2016

A Possible Pathogenic Linkage Among Headache, Migraine, and Nocturnal Enuresis in Children.

Pietro Ferrara, Livia Dell'Aquila, Giacomo Perrone, Giulia Spina, Francesco Miconi, Valentina Rapaccini, Ester Del Vescovo, Vincenzo Di Lazzaro, Alberto Verrotti

Abstract read
In one paragraph

Article in International neurourology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pietro FerraraInstitute of Pediatrics, Catholic University Medical School, Rome, Italy.ORCID 0000-0001-9449-3464
Livia Dell'AquilaService of Pediatrics Campus Bio-Medico University, Rome, Italy.
Giacomo PerroneService of Pediatrics Campus Bio-Medico University, Rome, Italy.
Giulia SpinaService of Pediatrics Campus Bio-Medico University, Rome, Italy.
Francesco MiconiService of Pediatrics Campus Bio-Medico University, Rome, Italy.
Valentina RapacciniInstitute of Neurology, Campus Bio-Medico University, Rome, Italy.
Ester Del VescovoService of Pediatrics Campus Bio-Medico University, Rome, Italy.
Vincenzo Di LazzaroInstitute of Neurology, Campus Bio-Medico University, Rome, Italy.
Alberto VerrottiDepartment of Pediatrics, University of Perugia, Perugia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to evaluate the prevalence of headaches and migraine in children with nocturnal enuresis (NE) and to improve knowledge on these conditions. In particular, for this purpose, a possible pathogenic relationship linking both conditions and the impact of headaches and migraine on NE persistence was evaluated.

methodsResearchers enrolled 123 children with NE, aged between 5 and 15 years, referred to the Service of Pediatrics, Campus Bio-Medico University Hospital of Rome between January 2014 and January 2015. Parents of all children enrolled in the study were invited to complete a self-reported questionnaire. The study protocol was approved by the Human Research Ethics Committee of Campus-Bio-Medico University. The NE group data was compared with the data of a control group (107 children).

resultsOf the eligible patients, 7.8% suffer from headaches/migraine (mean age, 9.63 years; interquartile range [IQR], 3.5 years) and 47.1% have a family history of headaches (mean age, 8.46 years; IQR, 3.75 years). Of the 8 patients with headaches, all are male, 3 have tension-type headaches (2 of them have maternal family history) and 5 have migraine (3 of them have maternal family history). Of the 35.3% with a migraine family history (mean age, 8.36 years; IQR, 3.5 years), 22 are male, and 14 are female. Three of these patients have migraine. A total of 92.2% suffer from NE but not from headaches (mean age, 8.43 years; IQR, 3 years). Of these patients, 33 are female (35.1%), and 61 are male (64.9%). In the control group, 4.7% (5 out of 107) of the children suffer from headaches, and of these, 4 are affected by nonmigraine headaches and 1 by migraine.

conclusionsIn conclusion, according to the hypothesis, NE and headaches/migraine could be linked by several similarities.

Indexed as

ChildEnuresisMelatonin

Identifiers

PMID28043109
PMCPMC5209575

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