Evidence map›Paper›PMID 28042860›Full record

ReviewSensors (Basel, Switzerland)2016

CMOS Electrochemical Instrumentation for Biosensor Microsystems: A Review.

Haitao Li, Xiaowen Liu, Lin Li, Xiaoyi Mu, Roman Genov, Andrew J Mason

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Review
  2. Review
  3. Advances in biosensors for bacterial detection and identification.World journal of microbiology & biotechnology · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Surface-modified CMOS biosensors.Frontiers in bioengineering and biotechnology · 2024
    Review
  12. Ultrasensitive Hierarchical AuNRs@SiOInternational journal of nanomedicine · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Aptasensor for the Detection ofBioengineering (Basel, Switzerland) · 2023
    Article
  17. Advances in Extracellular Vesicle Nanotechnology for Precision Theranostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haitao LiMaxim Integrated Products Inc., 160 Rio Robles, San Jose, CA 95134, USA. haitaoli7036@gmail.com.
Xiaowen LiuXcellcure LLC., 1 City Place Drive Suite 285, St. Louis, MO 63131, USA. liuxiaowen08@gmail.com.
Lin LiDepartment of Electrical and Computer Engineering, Michigan State University, East Lansing, MI 48824, USA. lilin02@gmail.com.
Xiaoyi MuApple Inc., 1 Infinite Loop, Cupertino, CA 95014, USA. muxiaoyi@gmail.com.
Roman GenovDepartment of Electrical and Computer Engineering, University of Toronto, Toronto, ON M5S, Canada. roman@eecg.toronto.edu.
Andrew J MasonDepartment of Electrical and Computer Engineering, Michigan State University, East Lansing, MI 48824, USA. mason@msu.edu.

Funding

Wearable Microsystem Array for Acute Pollutant Exposure AssessmentR01ES022302 · NIEHS · MICHIGAN STATE UNIVERSITY · PI MASON, ANDREW J, ZENG, XIANGQUN · 2014 to 2018
$2.3M
Rapid in-field malaria diagnosis, prognosis and monitoring using a mobile phoneR01AI113257 · NIAID · RICE UNIVERSITY · PI LILLEHOJ, PETER B · 2015 to 2018
$1.8M
NIAID NIH HHS R01 AI113257NIEHS NIH HHS R01 ES022302NIOSH CDC HHS R01 OH009644
6 · The paper itself

Abstract

Modern biosensors play a critical role in healthcare and have a quickly growing commercial market. Compared to traditional optical-based sensing, electrochemical biosensors are attractive due to superior performance in response time, cost, complexity and potential for miniaturization. To address the shortcomings of traditional benchtop electrochemical instruments, in recent years, many complementary metal oxide semiconductor (CMOS) instrumentation circuits have been reported for electrochemical biosensors. This paper provides a review and analysis of CMOS electrochemical instrumentation circuits. First, important concepts in electrochemical sensing are presented from an instrumentation point of view. Then, electrochemical instrumentation circuits are organized into functional classes, and reported CMOS circuits are reviewed and analyzed to illuminate design options and performance tradeoffs. Finally, recent trends and challenges toward on-CMOS sensor integration that could enable highly miniaturized electrochemical biosensor microsystems are discussed. The information in the paper can guide next generation electrochemical sensor design.

Indexed as

Biosensing TechniquesDielectric SpectroscopyElectrochemistryamperometrybiosensorcurrent readoutelectrochemicalimpedance spectroscopypotentiostat

Identifiers

PMID28042860
PMCPMC5298647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.