Evidence map›Paper›PMID 28042588›Full record

ReviewNeurophotonics2017

Review of the potential of optical technologies for cancer diagnosis in neurosurgery: a step toward intraoperative neurophotonics.

Fartash Vasefi, Nicholas MacKinnon, Daniel L Farkas, Babak Kateb

Open access · hybridAbstract readReview
In one paragraph

Review in Neurophotonics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 45 citations in OpenAlex.

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  17. Absorption by water increases fluorescence image contrast of biological tissue in the shortwave infrared.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Fartash VasefiSpectral Molecular Imaging Inc., 13412 Ventura Boulevard, Suite 250, Sherman Oaks, California 91423, United States; Brain Mapping Foundation, 8159 Santa Monica Boulevard, Suite 200, West Hollywood, California 90046, United States; Society for Brain Mapping and Therapeutics (SBMT), 8159 Santa Monica Boulevard, Suite 200, West Hollywood, California 90046, United States.
Nicholas MacKinnonSpectral Molecular Imaging Inc. , 13412 Ventura Boulevard, Suite 250, Sherman Oaks, California 91423, United States.
Daniel L FarkasSpectral Molecular Imaging Inc., 13412 Ventura Boulevard, Suite 250, Sherman Oaks, California 91423, United States; University of Southern California, Department of Biomedical Engineering, 1042 Downey Way, Los Angeles, California 90089, United States.
Babak KatebBrain Mapping Foundation, 8159 Santa Monica Boulevard, Suite 200, West Hollywood, California 90046, United States; Society for Brain Mapping and Therapeutics (SBMT), 8159 Santa Monica Boulevard, Suite 200, West Hollywood, California 90046, United States; California Neurosurgical Institute, 25751 McBean Pkwy #305, Santa Clarita, California 91355, United States; National Center for Nano-Bio-Electronics (NCNBE), NASA Research Park, P.O.Box 23, Moffett Field, California 94035, United States.
Brain Mapping Foundation · USUniversity of Southern California · US

Funding

Hyperspectral Imaging-Based Multimode Dermoscope For Early Melanoma DetectionR44CA183169 · NCI · SPECTRAL MOLECULAR IMAGING, INC. · PI FARKAS, DANIEL L · 2014 to 2016
$1.6M
NCI NIH HHS R44 CA183169
6 · The paper itself

Abstract

Advances in image-guided therapy enable physicians to obtain real-time information on neurological disorders such as brain tumors to improve resection accuracy. Image guidance data include the location, size, shape, type, and extent of tumors. Recent technological advances in neurophotonic engineering have enabled the development of techniques for minimally invasive neurosurgery. Incorporation of these methods in intraoperative imaging decreases surgical procedure time and allows neurosurgeons to find remaining or hidden tumor or epileptic lesions. This facilitates more complete resection and improved topology information for postsurgical therapy (i.e., radiation). We review the clinical application of recent advances in neurophotonic technologies including Raman spectroscopy, thermal imaging, optical coherence tomography, and fluorescence spectroscopy, highlighting the importance of these technologies in live intraoperative tissue mapping during neurosurgery. While these technologies need further validation in larger clinical trials, they show remarkable promise in their ability to help surgeons to better visualize the areas of abnormality and enable safe and successful removal of malignancies.

Indexed as

brain tumorimage-guided therapyintraoperative brain mappingneurophotonicsoptical imaging

Identifiers

PMID28042588
PMCPMC5184765
OpenAlexW2566542116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.