Evidence map›Paper›PMID 28042526›Full record

ArticleCurrent behavioral neuroscience reports2016

Cross-Disorder Psychiatric Genomics.

Anna R Docherty, Arden A Moscati, Ayman H Fanous

Abstract read
In one paragraph

Article in Current behavioral neuroscience reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Psychiatry in the Digital Age: A Blessing or a Curse?International journal of environmental research and public health · 2021
    Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anna R DochertyVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Arden A MoscatiVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Ayman H FanousVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA; Washington Veterans Affairs Healthcare System, Washington D.C., USA; Georgetown University School of Medicine, Washington D.C., USA.
Virginia Commonwealth University · US

Funding

Research Training: Psychiatric &Statistical GeneticsT32MH020030 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI HERMINE H MAES, MICHAEL CHURTON NEALE · 1999 to 2026
$6.7M
Research Education in Statistical Genetics of Substance AbuseR25DA026119 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI NEALE, MICHAEL CHURTON · 2008 to 2018
$3.2M
Modeling Dimensionality and Genetic Heterogeneity in SchizophreniaK01MH109765 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI DOCHERTY, ANNA R. · 2016 to 2019
$675k
An Association Study of Neurogenin 1 and SchizophreniaR03MH065622 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI FANOUS, AYMAN H · 2002 to 2002
$75k
Convergent Genetic and Genomic Analyses of Bipolar DisorderI01BX001242 · VA · U.S. DEPT/VETS AFFAIRS MEDICAL CENTER · PI FANOUS, AYMAN H · 2012 to 2015
–
Convergent Genetic and Genomic Analyses of SchizophreniaI01CX000278 · VA · U.S. DEPT/VETS AFFAIRS MEDICAL CENTER · PI FANOUS, AYMAN H · 2011 to 2014
–
BLRD VA I01 BX001242CSRD VA I01 CX000278Intramural VA VA999999NIDA NIH HHS R25 DA026119NIMH NIH HHS K01 MH109765NIMH NIH HHS R03 MH065622NIMH NIH HHS T32 MH020030
6 · The paper itself

Abstract

purpose of reviewThe following review provides some description of the movement in cross-disorder psychiatric genomics toward addressing both comorbidity and polygenicity. RECENT

findingsWe attempt to show how dimensional approaches to the phenotype have led to further addressing the problem of comorbidity of psychiatric diagnoses. And we also attempt to show how a dimensional approach to the genome, with different statistical methods from traditional genome-wide association analyses, has begun to resolve the problem of massive polygenicity. SUMMARY: Cross-disorder research, of any area in psychiatry, arguably has the most potential to inform clinical diagnosis, early detection and prevention strategies, and pharmacological treatment research. Future research might leverage what we now know to inform developmental studies of risk and resilience.

Indexed as

co-heritabilitycomorbiditycross-disordergeneticGWASpleiotropyPsychiatric Genomics Consortium

Identifiers

PMID28042526
PMCPMC5198908
OpenAlexW2468264542

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.