Evidence map›Paper›PMID 28042341›Full record

ArticleTheranostics2017

Anti-angiogenic Nanotherapy Inhibits Airway Remodeling and Hyper-responsiveness of Dust Mite Triggered Asthma in the Brown Norway Rat.

Gregory M Lanza, John Jenkins, Anne H Schmieder, Aigul Moldobaeva, Grace Cui, Huiying Zhang, Xiaoxia Yang, Qiong Zhong, Jochen Keupp, Ismail Sergin and 7 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Theranostics · 2021
    Article
  9. Article
  10. Inhalable nanotherapeutics to improve treatment efficacy for common lung diseases.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2020
    Review
  11. Emodin Alleviates the Airway Inflammation of Cough Variant Asthma in Mice by Regulating the Notch Pathway.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Gregory M LanzaDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
John JenkinsDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Anne H SchmiederDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Aigul MoldobaevaDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Grace CuiDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Huiying ZhangDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Xiaoxia YangDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Qiong ZhongDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Jochen KeuppPhilips Research Laboratories, Hamburg, Germany.
Ismail SerginDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Krishna S ParanandiDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Lindsey EldridgeDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.
John S AllenDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Todd WilliamsDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Michael J ScottDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Babak RazaniDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Elizabeth M WagnerDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Washington University in St. Louis · USJohns Hopkins University · USJohns Hopkins Medicine · USPhilips (Germany) · DE

Funding

Project 2 - Radiation-Induced Treatment of Multiple Myeloma using NanoparticlesU54CA199092 · NCI · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2015 to 2019
$11.5M
THE ROLE OF MACROPHAGE LYSOSOMAL BIOGENESIS IN ATHEROSCLEROSISR01HL125838 · NHLBI · WASHINGTON UNIVERSITY · PI RAZANI, BABAK · 2015 to 2025
$4.6M
Theranostic Approach to Asthma Using Anti-Angiogenic NanomedicineR01HL113392 · NHLBI · WASHINGTON UNIVERSITY · PI LANZA, GREGORY M, WAGNER, ELIZABETH · 2012 to 2016
$3.3M
NCI NIH HHS U54 CA199092NHLBI NIH HHS R01 HL113392NHLBI NIH HHS R01 HL125838
6 · The paper itself

Abstract

Although angiogenesis is a hallmark feature of asthmatic inflammatory responses, therapeutic anti-angiogenesis interventions have received little attention.

Indexed as

Airway RemodelingAngiogenesis InhibitorsAnimalsAsthmaCyclohexanesDisease Models, AnimalDocetaxelDrug CarriersFatty Acids, UnsaturatedMagnetic Resonance ImagingMicroscopy, FluorescenceNanostructuresProdrugsPyroglyphidaeRatsSesquiterpenesAngiogenesis InhibitorsCyclohexanesDocetaxelDrug CarriersFatty Acids, UnsaturatedfumagillinProdrugsSesquiterpenesTaxoidsAngiogenesisAsthmaFluorine MRINanomedicineProdrugRespiratory function

Identifiers

PMID28042341
PMCPMC5197071
OpenAlexW2566969105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.