Evidence map›Paper›PMID 28042338›Full record

ArticleTheranostics2017

Tumor Stiffening, a Key Determinant of Tumor Progression, is Reversed by Nanomaterial-Induced Photothermal Therapy.

Iris Marangon, Amanda A K Silva, Thomas Guilbert, Jelena Kolosnjaj-Tabi, Carmen Marchiol, Sharuja Natkhunarajah, Foucault Chamming's, Cécilia Ménard-Moyon, Alberto Bianco, Jean-Luc Gennisson and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Article
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  7. Phototherapy in cancer treatment: strategies and challenges.Signal transduction and targeted therapy · 2025
    Review
  8. Softness-Aided Mild Hyperthermia Boosts Stiff Nanomedicine by Regulating Tumor Mechanics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  9. Article
  10. Review
  11. [Research Progress on the Influence of Tumor Extracellular Matrix Mechanic Properties on Nanodrug Delivery].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Iris MarangonLaboratoire Matière et Systèmes Complexes (MSC), CNRS-UMR 7057, Université Paris Diderot, Sorbonne Paris Cité, 10 rue Alice Domon et Léonie Duquet, F-75205 Paris Cedex 13, France.
Amanda A K SilvaLaboratoire Matière et Systèmes Complexes (MSC), CNRS-UMR 7057, Université Paris Diderot, Sorbonne Paris Cité, 10 rue Alice Domon et Léonie Duquet, F-75205 Paris Cedex 13, France.
Thomas GuilbertPlateforme Imagerie, Institut Cochin, Inserm U1016-CNRS UMR8104-Université Paris Descartes, Sorbonne Paris Cité Paris, 22 rue Méchain, 75014 Paris France.
Jelena Kolosnjaj-TabiLaboratoire Matière et Systèmes Complexes (MSC), CNRS-UMR 7057, Université Paris Diderot, Sorbonne Paris Cité, 10 rue Alice Domon et Léonie Duquet, F-75205 Paris Cedex 13, France.
Carmen MarchiolPlateforme Imagerie, Institut Cochin, Inserm U1016-CNRS UMR8104-Université Paris Descartes, Sorbonne Paris Cité Paris, 22 rue Méchain, 75014 Paris France.
Sharuja NatkhunarajahPlateforme Imagerie, Institut Cochin, Inserm U1016-CNRS UMR8104-Université Paris Descartes, Sorbonne Paris Cité Paris, 22 rue Méchain, 75014 Paris France.
Foucault Chamming'sPARCC, Inserm U970, Paris Cardiovascular Research Center-PARCC / Université Paris-Descartes, Sorbonne Paris Cité, 56 rue Leblanc, 75015, Paris, France.
Cécilia Ménard-MoyonUniversity of Strasbourg, CNRS, Immunopathology and Therapeutic Chemistry, UPR 3572, 67000 Strasbourg, France.
Alberto BiancoUniversity of Strasbourg, CNRS, Immunopathology and Therapeutic Chemistry, UPR 3572, 67000 Strasbourg, France.
Jean-Luc GennissonInstitut Langevin, CNRS-UMR 7587, 1 place Jussieu, 75205 Paris, France.
Gilles RenaultPlateforme Imagerie, Institut Cochin, Inserm U1016-CNRS UMR8104-Université Paris Descartes, Sorbonne Paris Cité Paris, 22 rue Méchain, 75014 Paris France.
Florence GazeauLaboratoire Matière et Systèmes Complexes (MSC), CNRS-UMR 7057, Université Paris Diderot, Sorbonne Paris Cité, 10 rue Alice Domon et Léonie Duquet, F-75205 Paris Cedex 13, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor stiffening, stemming from aberrant production and organization of extracellular matrix (ECM), has been considered a predictive marker of tumor malignancy, non-invasively assessed by ultrasound shear wave elastography (SWE). Being more than a passive marker, tumor stiffening restricts the delivery of diagnostic and therapeutic agents to the tumor and

Indexed as

AnimalsAntineoplastic AgentsCarcinoma, Squamous CellDisease Models, AnimalElasticity Imaging TechniquesHeterograftsHyperthermia, InducedLasersMiceNanostructuresNanotubes, CarbonPhotochemotherapyAntineoplastic AgentsNanotubes, Carboncancercarbon nanotubeselastographyphotothermal therapytumor microenvironment.

Identifiers

PMID28042338
PMCPMC5197068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.