Evidence map›Paper›PMID 28042188›Full record

ArticleJournal of the American Statistical Association2016

Structured Matrix Completion with Applications to Genomic Data Integration.

Tianxi Cai, T Tony Cai, Anru Zhang

Abstract read
In one paragraph

Article in Journal of the American Statistical Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Representation Retrieval Learning for Heterogeneous Data Integration.Journal of the American Statistical Association · 2026
    Article
  2. Article
  3. Article
  4. Graphical Model Inference with Erosely Measured Data.Journal of the American Statistical Association · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
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  11. Sample-wise Combined Missing Effect Model with Penalization.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2023
    Article
  12. Generalized Liquid Association Analysis for Multimodal Data Integration.Journal of the American Statistical Association · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Simultaneous Covariance Inference for Multimodal Integrative Analysis.Journal of the American Statistical Association · 2020
    Article
  18. Article
  19. Article
  20. Structured Matrix Completion with Applications to Genomic Data Integration.Journal of the American Statistical Association · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tianxi CaiProfessor of Biostatistics, Department of Biostatistics, Harvard University, Boston, MA.
T Tony CaiDorothy Silberberg Professor of Statistics, Department of Statistics, The Wharton School, University of Pennsylvania, Philadelphia, PA.
Anru ZhangStudent, Department of Statistics, The Wharton School, University of Pennsylvania, Philadelphia, PA.

Funding

TrainingU54HG007963 · NHGRI · HARVARD MEDICAL SCHOOL · PI KOHANE, ISAAC S., MURPHY, SHAWN N · 2014 to 2018
$18.3M
Methods for genomic data with graphical structuresR01CA127334 · NCI · UNIVERSITY OF PENNSYLVANIA · PI LEE, HONGZHE · 2007 to 2016
$2.6M
Robust Approaches to the Development and Evaluation of Prognostic ClassifiersR01GM079330 · NIGMS · HARVARD SCHOOL OF PUBLIC HEALTH · PI CAI, TIANXI · 2007 to 2014
$1.0M
NCI NIH HHS R01 CA127334NHGRI NIH HHS U54 HG007963NIGMS NIH HHS R01 GM079330
6 · The paper itself

Abstract

Matrix completion has attracted significant recent attention in many fields including statistics, applied mathematics and electrical engineering. Current literature on matrix completion focuses primarily on independent sampling models under which the individual observed entries are sampled independently. Motivated by applications in genomic data integration, we propose a new framework of structured matrix completion (SMC) to treat structured missingness by design. Specifically, our proposed method aims at efficient matrix recovery when a subset of the rows and columns of an approximately low-rank matrix are observed. We provide theoretical justification for the proposed SMC method and derive lower bound for the estimation errors, which together establish the optimal rate of recovery over certain classes of approximately low-rank matrices. Simulation studies show that the method performs well in finite sample under a variety of configurations. The method is applied to integrate several ovarian cancer genomic studies with different extent of genomic measurements, which enables us to construct more accurate prediction rules for ovarian cancer survival.

Indexed as

Constrained minimizationgenomic data integrationlow-rank matrixmatrix completionsingular value decompositionstructured matrix completion

Identifiers

PMID28042188
PMCPMC5198844

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.