Evidence map›Paper›PMID 28042141›Full record

ArticleThe American journal of case reports2017

Prolonged Unexplained Hypoxemia as Initial Presentation of Cirrhosis: A Case Report.

Anand Puttappa, Kumaraswamy Sheshadri, Aurelie Fabre, Georgina Imberger, John Boylan, Silke Ryan, Masood Iqbal, Niamh Conlon

Open access · hybridAbstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. An Unusual Case of Refractory Hypoxia on the ICU.Case reports in critical care · 2018
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Anand PuttappaDepartment of Anaesthesia and Intensive Care, St Vincent's University Hospital, Dublin, Ireland.
Kumaraswamy SheshadriDepartment of Anaesthesia and Intensive Care, St Vincent's University Hospital, Dublin, Ireland.
Aurelie FabreDepartment of Histopathology, St Vincent's University Hospital, Dublin, Ireland.
Georgina ImbergerDepartment of Anaesthesia and Pain Medicine, Western Health, Melbourne, Australia.
John BoylanDepartment of Anaesthesia and Intensive Care, St Vincent's University Hospital, Dublin, Ireland.
Silke RyanDepartment of Respiratory and Sleep Medicine, St Vincent's University Hospital, Dublin, Ireland.
Masood IqbalDepartment of Hepatology, St Vincent's University Hospital, Dublin, Ireland.
Niamh ConlonDepartment of Anaesthesia and Intensive Care, St Vincent's University Hospital, Dublin, Ireland.
St. Vincent's University Hospital · IEWestern Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Hepatopulmonary syndrome (HPS) is a pulmonary complication of advanced liver disease with dyspnea as the predominant presenting symptom. The diagnosis of HPS can often be missed due to its nonspecific presentation and the presence of other comorbidities. CASE REPORT We present an interesting case of an obese 43-year-old man who presented with progressive, unexplained hypoxemia and shortness of breath in the absence of any symptoms or signs of chronic liver disease. After extensive cardiopulmonary investigations, he was diagnosed with severe HPS as a result of non-alcoholic steatohepatitis (NASH) leading to cirrhosis. He subsequently underwent successful hepatic transplantation and continues to improve at 12-month follow-up. CONCLUSIONS HPS needs to be considered in the differential diagnosis of unexplained hypoxemia. Given its poor prognosis, early diagnosis is warranted and treatment with liver transplantation is the preferred choice.

Indexed as

AdultBody Mass IndexDiagnosis, DifferentialHepatopulmonary SyndromeHumansHypoxiaLiver CirrhosisLiver TransplantationMaleObesityRisk FactorsTreatment Outcome

Identifiers

PMID28042141
PMCPMC5221740
OpenAlexW2565019673

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.