Evidence map›Paper›PMID 28041933›Full record

ArticleFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2017

A risk assessment of dietary Ochratoxin a in the United States.

Nicole J Mitchell, Chen Chen, Jeffrey D Palumbo, Andreia Bianchini, Jack Cappozzo, Jayne Stratton, Dojin Ryu, Felicia Wu

Open access · greenAbstract read
In one paragraph

Article in Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
12.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Article
  7. Reusable thiol-modificationFood chemistry: X · 2024
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Ochratoxin A and 2'Molecules (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Ochratoxin A-Induced Nephrotoxicity: Up-to-Date Evidence.International journal of molecular sciences · 2021
    Review
  17. Review
  18. Risk assessment of ochratoxin A in food.EFSA journal. European Food Safety Authority · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nicole J MitchellDepartment of Food Science and Human Nutrition, Michigan State University, 469 Wilson Rd. East Lansing, MI 48824, USA.
Chen ChenDepartment of Food Science and Human Nutrition, Michigan State University, 469 Wilson Rd. East Lansing, MI 48824, USA.
Jeffrey D PalumboU.S. Department of Agriculture, Agricultural Research Service, Foodborne Toxin Detection and Prevention Research Unit, 800 Buchanan St., Albany, CA 94710, USA.
Andreia BianchiniThe Food Processing Center, University of Nebraska-Lincoln, 248 Food Innovation Center Lincoln, NE 68588, USA.
Jack CappozzoIDF, Inc. 3801 E. Sunshine St., Springfield, MO 65808, USA.
Jayne StrattonThe Food Processing Center, University of Nebraska-Lincoln, 248 Food Innovation Center Lincoln, NE 68588, USA.
Dojin RyuSchool of Food Science, University of Idaho, 875 Perimeter Dr. Moscow, ID 83844, USA.
Felicia WuDepartment of Food Science and Human Nutrition, Michigan State University, 469 Wilson Rd. East Lansing, MI 48824, USA. Electronic address: fwu@msu.edu.
Michigan State University · USUniversity of Nebraska–Lincoln · USAgricultural Research Service · USUniversity of Idaho · US

Funding

The Effect of Aflatoxin Regulation on Global Liver Cancer RisksR01CA153073 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WU, FELICIA · 2010 to 2013
$916k
NCI NIH HHS R01 CA153073
6 · The paper itself

Abstract

Ochratoxin A (OTA) is a mycotoxin (fungal toxin) found in multiple foodstuffs. Because OTA has been shown to cause kidney disease in multiple animal models, several governmental bodies around the world have set maximum allowable levels of OTA in different foods and beverages. In this study, we conducted the first exposure and risk assessment study of OTA for the United States' population. A variety of commodities from grocery stores across the US were sampled for OTA over a 2-year period. OTA exposure was calculated from the OTA concentrations in foodstuffs and consumption data for different age ranges. We calculated the margin of safety (MOS) for individual age groups across all commodities of interest. Most food and beverage samples were found to have non-detectable OTA; however, some samples of dried fruits, breakfast cereals, infant cereals, and cocoa had detectable OTA. The lifetime MOS in the US population within the upper 95% of consumers of all possible commodities was >1, indicating negligible risk. In the US, OTA exposure is highest in infants and young children who consume large amounts of oat-based cereals. Even without OTA standards in the US, exposures would not be associated with significant risk of adverse effects.

Indexed as

DietAdolescentAdultAgedAged, 80 and overChildChild, PreschoolChromatography, LiquidFemaleFood ContaminationHumansInfantInfant, NewbornMaleMiddle AgedMycotoxinsMycotoxinsOchratoxins

Identifiers

PMID28041933
PMCPMC5292207
OpenAlexW2567665003

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.