ArticleAnnals of emergency medicine2017
Interpretation of Cerebrospinal Fluid White Blood Cell Counts in Young Infants With a Traumatic Lumbar Puncture.
Article in Annals of emergency medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Cerebrospinal Procalcitonin for Diagnosing Meningitis in Infants Less Than 90 Days: A Systematic Review and Meta-analysis.Indian pediatrics · 2025Pooled it
- A nomogram to predict probable meningitis in very preterm and/or very low birth weight infants with early-onset sepsis: a multicenter retrospective study.BMC pregnancy and childbirth · 2026Article
- Clinical Utility of CSF Correction Factors for Traumatic Lumbar Puncture in Adults.Neurology. Clinical practice · 2024Article
- Utility of cell index in the diagnosis of healthcare-associated ventriculitis and meningitis: an analytical cross-sectional study.BMC infectious diseases · 2024Observational
- Neurological Symptoms and Cause of Death Among Young Children in Low- and Middle-Income Countries.JAMA network open · 2024Article
- Management of well-appearing febrile young infants aged ≤90 days.Paediatrics & child health · 2024Review
- La prise en charge des nourrissons de 90 jours ou moins, fiévreux mais dans un bon état général.Paediatrics & child health · 2024Review
- Article
- A previous champagne tap reduces the probability of traumatic lumbar puncture in the following procedure.Scientific reports · 2023Article
- Effect of Spontaneous Subarachnoid Hemorrhage on Cerebrospinal Fluid Indicators.Brain sciences · 2023Article
- Detection of enterovirus in cerebrospinal fluids without pleocytosis in febrile infants under 3 months old reduces antibiotherapy duration.Frontiers in pediatrics · 2023Article
- Serious Bacterial Infections in Young Febrile Infants With Positive Urinalysis Results.Pediatrics · 2022Observational
- Interpretation of white blood cell counts in the cerebrospinal fluid of neonates with traumatic lumbar puncture: a retrospective cohort study.BMC pediatrics · 2022Observational
- Fc-MBL-modified FeMikrochimica acta · 2022Article
- Clinical utility of correction factors for febrile young infants with traumatic lumbar punctures.Paediatrics & child health · 2021Article
- Cost Analysis of Emergency Department Criteria for Evaluation of Febrile Infants Ages 29 to 90 Days.The Journal of pediatrics · 2021Article
- Caliber of lumbar puncture needle in preterm infants: few concerns.European journal of pediatrics · 2020Article
- Article
- Cerebrospinal Fluid Profiles of Infants ≤60 Days of Age With Bacterial Meningitis.Hospital pediatrics · 2019Article
- Etiology and Clinical Features of Full-Term Neonatal Bacterial Meningitis: A Multicenter Retrospective Cohort Study.Frontiers in pediatrics · 2019Article
Corrections and comments
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Authors and funding
13 authors at 9 institutions in 2 countries.
Funding
Abstract
STUDY
objectiveWe determine the optimal correction factor for cerebrospinal fluid WBC counts in infants with traumatic lumbar punctures.
methodsWe performed a secondary analysis of a retrospective cohort of infants aged 60 days or younger and with a traumatic lumbar puncture (cerebrospinal fluid RBC count ≥10,000 cells/mm
resultsOf the eligible 20,319 lumbar punctures, 2,880 (14%) were traumatic, and 33 of these patients (1.1%) had bacterial meningitis. The derived cerebrospinal fluid RBCs:WBCs ratio was 877:1 (95% confidence interval [CI] 805 to 961:1). Compared with the uncorrected cerebrospinal fluid WBC count, the corrected one had lower sensitivity for bacterial meningitis (88% uncorrected versus 67% corrected; difference 21%; 95% CI 10% to 37%) but resulted in fewer infants with cerebrospinal fluid pleocytosis (78% uncorrected versus 33% corrected; difference 45%; 95% CI 43% to 47%). Cerebrospinal fluid WBC count correction resulted in the misclassification of 7 additional infants with bacterial meningitis, who were misclassified as not having cerebrospinal fluid pleocytosis; only 1 of these infants was older than 28 days.
conclusionCorrection of the cerebrospinal fluid WBC count substantially reduced the number of infants with cerebrospinal fluid pleocytosis while misclassifying only 1 infant with bacterial meningitis of those aged 29 to 60 days.
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