Evidence map›Paper›PMID 28041633›Full record

ReviewTrends in neurosciences2017

Back to the Basics: Cnidarians Start to Fire.

Thomas C G Bosch, Alexander Klimovich, Tomislav Domazet-Lošo, Stefan Gründer, Thomas W Holstein, Gáspár Jékely, David J Miller, Andrea P Murillo-Rincon, Fabian Rentzsch, Gemma S Richards and 3 more

Abstract readReview
In one paragraph

Review in Trends in neurosciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

  1. Article
  2. Article
  3. Evaluating the Validity of Model Organisms: A Review and a New Framework for Biologists.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  4. Developing broad brains: the importance of an early introduction to evolutionary thinking in undergraduate neuroscience programs.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. A chromosome-level genome assembly for the colonial marine hydrozoanbioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Diffuse pacemaker mechanism with distinctive organization drives pulsation in the octocoralProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. The social origins of consciousness.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  14. Beyond synapses: cytoplasmic connections in brain function and evolution.Biological reviews of the Cambridge Philosophical Society · 2025
    Review
  15. Review
  16. Article
  17. Dynamics of neural activity in early nervous system evolution.Current opinion in behavioral sciences · 2024
    Article
  18. Review
  19. Review
  20. Sea anemones (Proceedings. Biological sciences · 2024
    Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Thomas C G BoschUniversity of Kiel, Kiel, Germany. Electronic address: tbosch@zoologie.uni-kiel.de.
Alexander KlimovichUniversity of Kiel, Kiel, Germany.
Tomislav Domazet-LošoRuđer Bošković Institute, Zagreb, Croatia; Catholic University of Croatia, Zagreb, Croatia.
Stefan GründerInstitute of Physiology, RWTH Aachen University, Germany.
Thomas W HolsteinCentre for Organismal Studies, Heidelberg, Germany.
Gáspár JékelyMax Planck Institute for Developmental Biology, Tübingen, Germany.
David J MillerARC Centre of Excellence for Coral Reef Studies, Townsville, Australia.
Andrea P Murillo-RinconUniversity of Kiel, Kiel, Germany.
Fabian RentzschSars International Centre for Marine Molecular Biology, University of Bergen, Norway.
Gemma S RichardsSars International Centre for Marine Molecular Biology, University of Bergen, Norway; University of Queensland, Brisbane, Australia.
Katja SchröderUniversity of Kiel, Kiel, Germany.
Ulrich TechnauUniversity of Vienna, Wien, Austria.
Rafael YusteNeurotechnology Center, Columbia University, New York, NY, USA. Electronic address: rafaelyuste@columbia.edu.

Funding

Functional connectomics of the neocortical microcircuitDP1EY024503 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 2013 to 2017
$4.0M
NEI NIH HHS DP1 EY024503
6 · The paper itself

Abstract

The nervous systems of cnidarians, pre-bilaterian animals that diverged close to the base of the metazoan radiation, are structurally simple and thus have great potential to reveal fundamental principles of neural circuits. Unfortunately, cnidarians have thus far been relatively intractable to electrophysiological and genetic techniques and consequently have been largely passed over by neurobiologists. However, recent advances in molecular and imaging methods are fueling a renaissance of interest in and research into cnidarians nervous systems. Here, we review current knowledge on the nervous systems of cnidarian species and propose that researchers should seize this opportunity and undertake the study of members of this phylum as strategic experimental systems with great basic and translational relevance for neuroscience.

Indexed as

AnimalsAxonsBiological EvolutionCnidariaHumansNervous SystemNeuronsNeurotransmitter AgentsNeurotransmitter AgentsBRAIN InitiativeCRISPRHydraimagingNematostella

Identifiers

PMID28041633
PMCPMC5285349

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.