Evidence map›Paper›PMID 28041591›Full record

ArticleMaturitas2017

Hot flashes and midlife symptoms in relation to levels of salivary cortisol.

Linda M Gerber, Lynnette L Sievert, Joseph E Schwartz

Abstract read
In one paragraph

Article in Maturitas, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. 'When my autism broke': A qualitative study spotlighting autistic voices on menopause.Autism : the international journal of research and practice · 2020
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Linda M GerberDepartment of Healthcare Policy & Research, Division of Biostatistics and Epidemiology, Weill Cornell Medical College, United States; Department of Medicine, Division of Nephrology & Hypertension, Weill Cornell Medical College, United States. Electronic address: lig2002@med.cornell.edu.
Lynnette L SievertDepartment of Anthropology, University of Massachusetts Amherst, United States.
Joseph E SchwartzCenter for Behavioral Cardiovascular Health, Columbia University, United States; Department of Psychiatry, Stony Brook University, United States.

Funding

VEGF VECTOR TO ISCHEMIC MYOCARDIUM W/DIFFUSE CORONARY DISEASEM01RR000047 · NCRR · WEILL MEDICAL COLL OF CORNELL UNIV · PI MCQUIGGAN, MARGARET M · 1985 to 2007
$36.4M
WORKSITE BLOOD PRESSURE STUDYP01HL047540 · NHLBI · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI SLOAN, RICHARD P · 1993 to 2014
$27.7M
MIND-BODY-BEHAVIORAL MED CLINICAL TRIALS INFRASTRUCTURER24HL076857 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI OGEDEGBE, OLUGBENGA G. · 2004 to 2008
$3.5M
NCRR NIH HHS M01 RR000047NHLBI NIH HHS P01 HL047540NHLBI NIH HHS R24 HL076857
6 · The paper itself

Abstract

objectivesThis study examined the relationship between salivary cortisol levels and hot flashes during midlife. Previous studies have shown that cortisol levels increase with hot flashes in the laboratory, and higher cortisol levels have been associated with more severe hot flashes. Salivary cortisol levels were also examined in relation to total number of midlife symptoms.

methodsWomen aged 40-60 years (n=109) reported the presence or absence of 23 symptoms, including hot flashes, during the previous 2 weeks. Salivary samples were collected at waking, 30min after waking, 1h before bedtime, and at bedtime. The cortisol awakening response (CAR), cortisol daily decline (CDD), log transformed salivary cortisol levels at each time point, and mean cortisol levels were compared by hot flash report using t-tests. Logistic regression analyses were performed to assess the association between each cortisol measure and the presence or absence of hot flashes, after controlling for potential covariates.

resultsSalivary cortisol levels were not significantly associated with hot flashes or sum of symptoms. Hot flash report did not differentiate women who had a positive CAR from those who did not, or women who showed strong CDD from those who did not.

conclusionSymptomatic women - defined by hot flash report or symptom total - were not found to have higher salivary cortisol levels.

Indexed as

AdultFemaleHot FlashesHumansHydrocortisoneMenopauseMiddle AgedSalivaTime FactorsHydrocortisoneHot flashesHot flushesMenopauseSalivary cortisolStress

Identifiers

PMID28041591
PMCPMC5215844

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.