Evidence map›Paper›PMID 28040848›Full record

ArticleFood and environmental virology2017

New Proof-of-Concept in Viral Inactivation: Virucidal Efficacy of 405 nm Light Against Feline Calicivirus as a Model for Norovirus Decontamination.

Rachael M Tomb, Michelle Maclean, John E Coia, Elizabeth Graham, Michael McDonald, Chintamani D Atreya, Scott J MacGregor, John G Anderson

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in Food and environmental virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026
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  11. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022
    Article
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  13. Pulsed blue light, saliva and curcumin significantly inactivate human coronavirus.Journal of photochemistry and photobiology. B, Biology · 2022
    Article
  14. Review
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  19. Pulsed blue light inactivates two strains of human coronavirus.Journal of photochemistry and photobiology. B, Biology · 2021
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Rachael M TombThe Robertson Trust Laboratory for Electronic Sterilisation Technologies (ROLEST), Department of Electronic & Electrical Engineering, University of Strathclyde, Royal College Building, 204 George Street, Glasgow, G1 1XW, Scotland, UK. rachael.tomb.2013@uni.strath.ac.uk.
Michelle MacleanThe Robertson Trust Laboratory for Electronic Sterilisation Technologies (ROLEST), Department of Electronic & Electrical Engineering, University of Strathclyde, Royal College Building, 204 George Street, Glasgow, G1 1XW, Scotland, UK.
John E CoiaDepartment of Clinical Microbiology, Glasgow Royal Infirmary, Glasgow, Scotland, UK.
Elizabeth GrahamSchool of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK.
Michael McDonaldSchool of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK.
Chintamani D AtreyaOffice of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD, USA.
Scott J MacGregorThe Robertson Trust Laboratory for Electronic Sterilisation Technologies (ROLEST), Department of Electronic & Electrical Engineering, University of Strathclyde, Royal College Building, 204 George Street, Glasgow, G1 1XW, Scotland, UK.
John G AndersonThe Robertson Trust Laboratory for Electronic Sterilisation Technologies (ROLEST), Department of Electronic & Electrical Engineering, University of Strathclyde, Royal College Building, 204 George Street, Glasgow, G1 1XW, Scotland, UK.
University of Strathclyde · GBUniversity of Glasgow · GBCenter for Biologics Evaluation and Research · USGlasgow Royal Infirmary · GBThe Robertson Trust · GB

Funding

Chief Scientist Office SIRN/DTF/13/02
6 · The paper itself

Abstract

The requirement for novel decontamination technologies for use in hospitals is ever present. One such system uses 405 nm visible light to inactivate microorganisms via ROS-generated oxidative damage. Although effective for bacterial and fungal inactivation, little is known about the virucidal effects of 405 nm light. Norovirus (NoV) gastroenteritis outbreaks often occur in the clinical setting, and this study was designed to investigate potential inactivation effects of 405 nm light on the NoV surrogate, feline calicivirus (FCV). FCV was exposed to 405 nm light whilst suspended in minimal and organically-rich media to establish the virucidal efficacy and the effect biologically-relevant material may play in viral susceptibility. Antiviral activity was successfully demonstrated with a 4 Log

Indexed as

AnimalsCaliciviridae InfectionsCalicivirus, FelineCatsCell LineDecontaminationDisinfectantsHumansLightModels, BiologicalNorovirusVirus InactivationDisinfectants405 nm LightFaecesFeline calicivirusPlasmaSalivaViral inactivation

Identifiers

PMID28040848
PMCPMC5429381
OpenAlexW2564437482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.