Evidence map›Paper›PMID 28040607›Full record

ArticleJournal of the mechanical behavior of biomedical materials2017

Investigation of inhomogeneous and anisotropic material behavior of porcine thoracic aorta using nano-indentation tests.

Golriz Kermani, Ali Hemmasizadeh, Soroush Assari, Michael Autieri, Kurosh Darvish

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. [Experimental study on mechanical properties of the ventral and the dorsal tissues of porcine descending aorta].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2019
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Golriz KermaniDepartment of Mechanical Engineering, College of Engineering, Temple University, 1947 N. 12th Street, Philadelphia, PA 19122, United States.
Ali HemmasizadehDepartment of Mechanical Engineering, College of Engineering, Temple University, 1947 N. 12th Street, Philadelphia, PA 19122, United States.
Soroush AssariDepartment of Mechanical Engineering, College of Engineering, Temple University, 1947 N. 12th Street, Philadelphia, PA 19122, United States.
Michael AutieriDepartment of Physiology, School of Medicine, Temple University, 3500 N. Broad Street, Philadelphia, PA 19140, United States.
Kurosh DarvishDepartment of Mechanical Engineering, College of Engineering, Temple University, 1947 N. 12th Street, Philadelphia, PA 19122, United States. Electronic address: kdarvish@temple.edu.
Temple University · US

Funding

miRNA-mediated reduction of VSMC foam cell formationR01HL117724 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI AUTIERI, MICHAEL V · 2013 to 2022
$3.8M
Attenuation of atherosclerosis by regulation of VSMC inflammatory gene mRNA stabilityR01HL141108 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI AUTIERI, MICHAEL V · 2018 to 2021
$2.0M
Mechanisms of Traumatic Rupture in ArteriesK25HL086512 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI DARVISH, KUROSH K · 2008 to 2012
$729k
Development of Experimental and Computational Models for Traumatic Aortic RuptureR21HL088159 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI DARVISH, KUROSH K · 2008 to 2009
$400k
NHLBI NIH HHS K25 HL086512NHLBI NIH HHS R01 HL117724NHLBI NIH HHS R01 HL141108NHLBI NIH HHS R21 HL088159
6 · The paper itself

Abstract

This study investigates the inhomogeneity and anisotropy of porcine descending thoracic aorta in three dimensions using a custom-made nano-indentation technique and a quasi-linear viscoelastic modeling approach. The indentation tests were conducted in axial, circumferential, and radial orientations with about 100 μm spatial resolution. The ratio of the elastic moduli obtained in different orientations was used to quantify the tissue local anisotropy. The distal sections were generally stiffer than the proximal ones in both axial and circumferential indentations. Four distinct layers were identified across the thickness with significantly different mechanical properties. The stiffness of the medial quadrant was significantly lower than all other quadrants in axial indentation. The anisotropic behavior of the tissue was more pronounced in the lateral quadrant of the distal sections. The results of this study can be used to better understand the mechanisms of aorta deformation and improve the spatial accuracy of computational models of aorta.

Indexed as

AnisotropyStress, MechanicalAnimalsAorta, ThoracicBiomechanical PhenomenaElastic ModulusSwineAnisotropyAorta material propertiesInhomogeneityNano-indentationThoracic aortaViscoelasticity

Identifiers

PMID28040607
PMCPMC5359050
OpenAlexW2563002844

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.