ReviewMechanisms of ageing and development2017
Demographics, phenotypic health characteristics and genetic analysis of centenarians in China.
Review in Mechanisms of ageing and development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
58 citing papers in PubMed, 147 citations in OpenAlex.
- Article
- Association of comorbid depressive and anxiety symptoms with cognitive impairment and dementia in Chinese elderly people.BMC psychiatry · 2026Article
- Healthy Lifestyle, multimorbidity network, and all-cause mortality among older Chinese: a longitudinal analysis in Chinese longitudinal healthy longevity survey.BMC public health · 2026Article
- Associations of changes in waist-to-height ratio with all-cause mortality among Chinese older adults: a national cohort study.Frontiers in nutrition · 2026Article
- Associations of protein-enriched dietary diversity, anti-inflammatory dietary diversity, and low muscle mass among older Chinese adults: a nationwide cross-sectional analysis.BMC geriatrics · 2025Article
- Association between residential proximity to major roadways and sleep health in older Chinese people: the moderating role of living environments.BMC public health · 2025Article
- Association between sensory impairment and cognitive frailty among older people: Evidence from four nationwide cohort studies.The journal of nutrition, health & aging · 2025Article
- Social isolation in relation to the incidence and dynamic progression of frailty in the oldest old: a trajectory analysis of a nationwide cohort.BMC public health · 2025Article
- Does the New Rural Cooperative Medical Scheme Provincial Pooling Policy Improve Health Equity Among Older Adults? - Evidence From China Longitudinal Healthy Longevity Survey Data.International journal of health policy and management · 2025Article
- Association of BMI trajectories and healthy aging among Chinese older adults: a national cohort study.Frontiers in public health · 2025Article
- Relationship between staple food types and cardiovascular disease risk among older Chinese adults.Frontiers in nutrition · 2025Article
- Network analysis of the relationships between depressive symptoms and social participation activities among Chinese older adults and its implications for nursing.International journal of nursing sciences · 2024Article
- Association of psychological resilience with all-cause and cause-specific mortality in older adults: a cohort study.BMC public health · 2024Article
- Loneliness shapes disparities in healthy life expectancy: a multi-state analysis from China.BMC public health · 2024Article
- Cognitive Function, Healthy Lifestyle, and All-Cause Mortality among Chinese Older Adults: A Longitudinal Prospective Study.Nutrients · 2024Article
- Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.BMC geriatrics · 2024Article
- Association between residential proximity to major roadways and chronic multimorbidity among Chinese older adults: a nationwide cross-sectional study.BMC geriatrics · 2024Article
- Cognitive trajectories and their relationships with education and diets among older adults: a network-based 10-year cohort study.Frontiers in aging neuroscience · 2024Article
- Famine exposure in early life increases risk of cataracts in elderly stage.Frontiers in nutrition · 2024Article
- Childhood and adult socioeconomic status influence on late-life healthy longevity: evidence from the Chinese longitudinal healthy longevity survey.Frontiers in public health · 2024Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
Abstract
After a brief introduction to the background, significance and unique features of the centenarian population in China, we describe the Chinese Longitudinal Healthy Longevity Study (CLHLS), which is the world's largest study of centenarians, nonagenarians, octogenarians, and compatible young-old aged 65-79. Based on the CLHLS data and other relevant studies, we summarize demographic and socioeconomic characteristics as well as self-reported and objectively-tested health indicators of centenarians in China, with an emphasis on gender differences and rural/urban disparities. We then compare five-year-age-specific trajectories of physical and cognitive functions, self-reported health, and life satisfactions from ages 65-69 to 100+, concluding that good psychological resilience and optimism are keys to the exceptional longevity enjoyed by centenarians. We discuss recent findings of novel loci and pathways that are significantly associated with longevity based on the genome-wide association study (GWAS) of the CLHLS centenarian sample, which is 2.7 times as large as prior GWAS of longevity. We also highlight colleagues' and our own studies on longevity candidate genes and gene-environment interaction analyses. Finally, we discuss limitations inherent in our studies of centenarians in China and further research perspectives.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.