Evidence map›Paper›PMID 28039878›Full record

ArticleBiopharmaceutics & drug disposition2017

Quantifying gut wall metabolism: methodology matters.

Oliver J D Hatley, Christopher R Jones, Aleksandra Galetin, Amin Rostami-Hodjegan

Abstract read
In one paragraph

Article in Biopharmaceutics & drug disposition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. A primary human Gut/Liver microphysiological system to estimate human oral bioavailability.Drug metabolism and disposition: the biological fate of chemicals · 2025
    Article
  3. Article
  4. Characterizing and Quantifying Extrahepatic Metabolism of (-)-ΔDrug metabolism and disposition: the biological fate of chemicals · 2022
    Article
  5. Prediction of Drug Clearance from Enzyme and Transporter Kinetics.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  6. Article
  7. Human Microphysiological Models of Intestinal Tissue and Gut Microbiome.Frontiers in bioengineering and biotechnology · 2020
    Review
  8. Article
  9. Quantifying gut wall metabolism: methodology matters.Biopharmaceutics & drug disposition · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Oliver J D HatleySimcyp Ltd (A Certara Company), Blades Enterprise Centre, Sheffield, S2 4SU, UK.
Christopher R JonesDMPK, Heptares, Welwyn Garden City, AL7 3AX, UK.
Aleksandra GaletinCentre for Applied Pharmacokinetic Research, Manchester Pharmacy School, University of Manchester, Manchester, M13 9PT, UK.
Amin Rostami-HodjeganSimcyp Ltd (A Certara Company), Blades Enterprise Centre, Sheffield, S2 4SU, UK.ORCID http://orcid.org/0000-0003-3917-844X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PharmacokineticsAnimalsHumansIntestinal MucosaIn Vitro TechniquesMicrosomes

Identifiers

PMID28039878
PMCPMC5412859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.