Evidence map›Paper›PMID 28039873›Full record

ArticleJournal of the American Geriatrics Society2017

Effect of Resting Heart Rate on All-Cause Mortality and Cardiovascular Events According to Age.

Kuibao Li, Chonghua Yao, Xinchun Yang, Lei Dong

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Initial in-hospital heart rate is associated with long-term survival in patients with acute ischemic stroke.Clinical research in cardiology : official journal of the German Cardiac Society · 2022
    Article
  4. Observational
  5. Article
  6. Article
  7. Genomics of Cardiovascular Measures of Autonomic Tone.Journal of cardiovascular pharmacology · 2018
    Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Kuibao LiHeart Center of Beijing, Chaoyang Hospital, Capital Medical University, Beijing, China.
Chonghua YaoBeijing Centers for Disease Control and Prevention, Anzhen Hospital, Capital Medical University, Beijing, China.
Xinchun YangHeart Center of Beijing, Chaoyang Hospital, Capital Medical University, Beijing, China.
Lei DongBeijing Centers for Disease Control and Prevention, Anzhen Hospital, Capital Medical University, Beijing, China.

Funding

Genetic Epidemiology of Blood Pressure InterventionU01HL072507 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI HE, JIANG · 2002 to 2008
$7.6M
NHLBI NIH HHS U01 HL072507
6 · The paper itself

Abstract

objectivesTo examine whether the association between resting heart rate (RHR) and all-cause mortality and cardiovascular events differs according to age.

designProspective cohort.

settingCommunity in Beijing, China.

participantsIndividuals aged 40 and older without cardiovascular disease at baseline (N = 6,209). MEASUREMENTS: Trained investigators interviewed participants using a standard questionnaire to obtain information on demographic characteristics, medical history and lifestyle risk factors in 1991. RHR was evaluated according to quartiles (<72, 72-76, 76-84, ≥84 beats/min). Cox regression models were used to assess the associations between RHR and all-cause mortality and cardiovascular events.

resultsDuring a mean follow-up of 8.3 years, 840 subjects died, and 676 experienced a cardiovascular event. Higher RHR was significantly associated with all-cause mortality (P trend < .001) and cardiovascular events (P trend = .002) in older (≥60) but not younger (<60) participants (both P trend > .05). There were significant modifying effects of age on the association between RHR and all-cause mortality (P interaction < .001) and cardiovascular events (P interaction =.002). Similar results were observed after exclusion of individuals who died (n = 100) or had a cardiovascular event (n = 45) during the first 2 years of follow-up.

conclusionHigh RHR appears to be an independent determinant of all-cause mortality and cardiovascular events in older but not younger individuals.

Indexed as

Life StyleAge FactorsCardiovascular DiseasesCause of DeathFemaleHeart RateHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesRisk FactorsSurveys and Questionnairescardiovascular diseasecohort studydeathepidemiologyresting heart rate

Identifiers

PMID28039873
PMCPMC5435540

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.