Evidence map›Paper›PMID 28039490›Full record

ArticleAging2016

Impaired fasting blood glucose is associated to cognitive impairment and cerebral atrophy in middle-aged non-human primates.

Fathia Djelti, Marc Dhenain, Jérémy Terrien, Jean-Luc Picq, Isabelle Hardy, Delphine Champeval, Martine Perret, Esther Schenker, Jacques Epelbaum, Fabienne Aujard

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Fathia DjeltiMECADEV UMR 7179, Centre National de la Recherche Scientifique, Muséum National d'Histoire Naturelle, 91800 Brunoy, France.
Marc DhenainCentre National de la Recherche Scientifique, Université Paris Sud, Université Paris Saclay, UMR 9199, Neurodegenerative Diseases Laboratory, 92265 Fontenay-aux-Roses, France.
Jérémy TerrienMECADEV UMR 7179, Centre National de la Recherche Scientifique, Muséum National d'Histoire Naturelle, 91800 Brunoy, France.
Jean-Luc PicqLaboratoire de Psychopathologie et de Neuropsychologie, EA 2027, Université Paris 8, 93200 Saint-Denis, France.
Isabelle HardyMECADEV UMR 7179, Centre National de la Recherche Scientifique, Muséum National d'Histoire Naturelle, 91800 Brunoy, France.
Delphine ChampevalMECADEV UMR 7179, Centre National de la Recherche Scientifique, Muséum National d'Histoire Naturelle, 91800 Brunoy, France.
Martine PerretMECADEV UMR 7179, Centre National de la Recherche Scientifique, Muséum National d'Histoire Naturelle, 91800 Brunoy, France.
Esther SchenkerInstitut de Recherches Servier, 78290 Croissy-sur-Seine, France.
Jacques EpelbaumMECADEV UMR 7179, Centre National de la Recherche Scientifique, Muséum National d'Histoire Naturelle, 91800 Brunoy, France.
Fabienne AujardMECADEV UMR 7179, Centre National de la Recherche Scientifique, Muséum National d'Histoire Naturelle, 91800 Brunoy, France.
Centre National de la Recherche Scientifique · FRCEA Paris-Saclay - Etablissement de Fontenay-aux-roses · FRInserm · FRMécanismes Adaptatifs et Evolution · FRServier (France) · FRUniversité Paris 8 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-associated cognitive impairment is a major health and social issue because of increasing aged population. Cognitive decline is not homogeneous in humans and the determinants leading to differences between subjects are not fully understood. In middle-aged healthy humans, fasting blood glucose levels in the upper normal range are associated with memory impairment and cerebral atrophy. Due to a close evolutional similarity to Man, non-human primates may be useful to investigate the relationships between glucose homeostasis, cognitive deficits and structural brain alterations. In the grey mouse lemur,

Indexed as

Age FactorsAnimalsAtrophyBlood GlucoseCerebral CortexCheirogaleidaeCognitive DysfunctionFastingFemaleOrgan SizeSpatial MemoryBlood Glucoseblood glucosehippocampal/septal atrophyMicrocebus murinusmiddle agespatial memory performancespontaneous models

Identifiers

PMID28039490
PMCPMC5310663
OpenAlexW2563116762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.