Evidence map›Paper›PMID 28039453›Full record

ArticleOncotarget2017

Comparison between ultra-high and conventional mono b-value DWI for preoperative glioma grading.

Yu-Chuan Hu, Lin-Feng Yan, Qian Sun, Zhi-Cheng Liu, Shu-Mei Wang, Yu Han, Qiang Tian, Ying-Zhi Sun, Dan-Dan Zheng, Wen Wang and 1 more

Abstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Integrated slice-specific dynamic shimming diffusion weighted imaging (DWI) for rectal Cancer detection and characterization.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Efficiency of High and StandardJournal of oncology · 2020
    Article
  12. Observational
  13. Review
  14. Article
  15. Article
  16. Article
  17. A Modified Tri-Exponential Model for Multi-Frontiers in neuroscience · 2018
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yu-Chuan HuDepartment of Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Lin-Feng YanDepartment of Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Qian SunDepartment of Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Zhi-Cheng LiuDepartment of Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Shu-Mei WangDepartment of Pathology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Yu HanDepartment of Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Qiang TianDepartment of Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Ying-Zhi SunDepartment of Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Dan-Dan ZhengMR Research China, GE Healthcare China, Beijing, China.
Wen WangDepartment of Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Guang-Bin CuiDepartment of Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compare the efficacy of ultra-high and conventional mono-b-value DWI for glioma grading, in 109 pathologically confirmed glioma patients, ultra-high apparent diffusion coefficient (ADCuh)was calculated using a tri-exponential mode, distributed diffusion coefficients (DDCs) and α values were calculated using a stretched-exponential model, and conventional ADC values were calculated using a mono-exponential model. The efficacy and reliability of parameters for grading gliomas were investigated using receiver operating characteristic (ROC) curve and intra-class correlation (ICC) analyses, respectively. The ADCuh values differed (P < 0.001) between low-grade gliomas (LGGs; 0.436 ×10-3 mm2/sec) and high-grade gliomas (HGGs; 0.285 × 10-3 mm2/sec). DDC, a and various conventional ADC values were smaller in HGGs (all P ≤ 0.001, vs. LGGs). The ADCuh parameter achieved the highest diagnostic efficacy with an area under curve (AUC) of 0.993, 92.9% sensitivity and 98.8% specificity for glioma grading at a cutoff value of 0.362×10-3 mm2/sec. ADCuh measurement appears to be an easy-to-perform technique with good reproducibility (ICC = 0.9391, P < 0.001). The ADCuh value based in a tri-exponential model exhibited greater efficacy and reliability than other DWI parameters, making it a promising technique for glioma grading.

Indexed as

AdolescentAdultAgedAged, 80 and overBrain NeoplasmsChildChild, PreschoolDiffusion Magnetic Resonance ImagingGliomaHumansMaleMiddle AgedNeoplasm GradingYoung Adultapparent diffusion coefficientdiffusion-weighted imaginggliomagradingMRI

Identifiers

PMID28039453
PMCPMC5514959

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.