Evidence map›Paper›PMID 28039266›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Malignant Astrocytic Tumor Progression Potentiated by JAK-mediated Recruitment of Myeloid Cells.

Prajwal Rajappa, William S Cobb, Emma Vartanian, Yujie Huang, Laura Daly, Caitlin Hoffman, Jane Zhang, Beiyi Shen, Rachel Yanowitch, Kunal Garg and 8 more

Registry-linked trialAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04852354 (Tissue Collection for Drug Screening and Bioanalysis), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04852354 recruitingnot on this mapstarted 2020, after this paper: background citation

Tissue Collection for Drug Screening and Bioanalysis

TypeobservationalSponsorWeill Medical College of Cornell UniversityRan2020 to 2029Enrolled500ConditionsCentral Nervous System Tumor
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Prajwal RajappaDepartment of Neurological Surgery, Weill Cornell Medical College, New York, New York.
William S CobbDepartment of Neurological Surgery, Weill Cornell Medical College, New York, New York.
Emma VartanianWeill Medical College of Cornell University, New York, New York.
Yujie HuangDepartment of Neurological Surgery, Weill Cornell Medical College, New York, New York.
Laura DalyDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Caitlin HoffmanDepartment of Neurological Surgery, Weill Cornell Medical College, New York, New York.
Jane ZhangDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Beiyi ShenWeill Medical College of Cornell University, New York, New York.
Rachel YanowitchDepartment of Neurological Surgery, Weill Cornell Medical College, New York, New York.
Kunal GargWeill Medical College of Cornell University, New York, New York.
Babacar CisseDepartment of Neurological Surgery, Weill Cornell Medical College, New York, New York.
Sara HaddockDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Jason HuseDepartment of Pathology and, Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York.
David J PisapiaWeill Cornell Medical College, Department of Pathology, Division of Neuropathology, New York, New York.
Timothy A ChanDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
David C LydenChildren's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, Cell and Developmental Biology, Weill Cornell Medical College, New York, New York.
Jacqueline F BrombergDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. bromberj@mskcc.org jpgreenf@med.cornell.edu.
Jeffrey P GreenfieldDepartment of Neurological Surgery, Weill Cornell Medical College, New York, New York. bromberj@mskcc.org jpgreenf@med.cornell.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAstrocytomaCD11b AntigenCell Line, TumorCell ProliferationDisease Models, AnimalDisease ProgressionFemaleHumansJanus Kinase 1MaleMiceMyeloid CellsNeovascularization, PathologicPyrazolesPyrimidinesAZD 1480CD11b AntigenITGAM protein, humanJanus Kinase 1PyrazolesPyrimidines

Identifiers

PMID28039266
PMCPMC5769921

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.