Evidence map›Paper›PMID 28039264›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Immunization against HIF-1α Inhibits the Growth of Basal Mammary Tumors and Targets Mammary Stem Cells

Denise L Cecil, Meredith Slota, Megan M O'Meara, Benjamin C Curtis, Ekram Gad, Yushe Dang, Daniel Herendeen, Lauren Rastetter, Mary L Disis

Abstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Breast cancer vaccines for treatment and prevention.Breast cancer research and treatment · 2022
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Hypoxia-Induced Phenotypes that Mediate Tumor Heterogeneity.Advances in experimental medicine and biology · 2019
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Denise L CecilTumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington. dcecil@uw.edu.
Meredith SlotaTumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington.
Megan M O'MearaSeattle Genetics, Inc., Bothell, Washington.
Benjamin C CurtisTumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington.
Ekram GadTumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington.
Yushe DangTumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington.
Daniel HerendeenTumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington.
Lauren RastetterTumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington.
Mary L DisisTumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington.
Seagen (United States) · US

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Institute of Translational Health SciencesUL1TR000423 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$49.4M
NCATS NIH HHS UL1 TR000423NCATS NIH HHS UL1 TR002319
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCancer VaccinesCell Line, TumorCell ProliferationFemaleHumansHypoxia-Inducible Factor 1, alpha SubunitImmunizationImmunoglobulin GMammary Neoplasms, AnimalMiceNeoplasm Recurrence, LocalNeoplastic Stem CellsTriple Negative Breast NeoplasmsCancer VaccinesHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitImmunoglobulin G

Identifiers

PMID28039264
PMCPMC5493515
OpenAlexW2564006575

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.