Evidence map›Paper›PMID 28039194›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2017

Sequence and functional characterization of hypoxia-inducible factors, HIF1α, HIF2αa, and HIF3α, from the estuarine fish,

Ian K Townley, Sibel I Karchner, Elena Skripnikova, Thomas E Wiese, Mark E Hahn, Bernard B Rees

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Hypoxia Tolerance of Two Killifish Species.Integrative and comparative biology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ian K TownleyDepartment of Biological Sciences, University of New Orleans, New Orleans, Louisiana.
Sibel I KarchnerBiology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts.
Elena SkripnikovaDepartment of Biological Sciences, University of New Orleans, New Orleans, Louisiana.
Thomas E WieseCollege of Pharmacy, Xavier University of New Orleans, New Orleans, Louisiana; and.
Mark E HahnBiology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts.
Bernard B ReesDepartment of Biological Sciences, University of New Orleans, New Orleans, Louisiana brees@uno.edu.
University of New Orleans · USWoods Hole Oceanographic Institution · USXavier University of Louisiana · US

Funding

Training CoreP42ES007381 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SHERR, DAVID H · 1995 to 2019
$46.1M
NIEHS NIH HHS P42 ES007381
6 · The paper itself

Abstract

The hypoxia-inducible factor (HIF) family of transcription factors plays central roles in the development, physiology, pathology, and environmental adaptation of animals. Because many aquatic habitats are characterized by episodes of low dissolved oxygen, fish represent ideal models to study the roles of HIF in the response to aquatic hypoxia. The estuarine fish

Indexed as

AnimalsBase SequenceBasic Helix-Loop-Helix ProteinsEstuariesFundulidaeMolecular Sequence DataSpecies SpecificityStructure-Activity RelationshipBasic Helix-Loop-Helix Proteinsenvironmental adaptationgene expressionoxygen

Identifiers

PMID28039194
PMCPMC5402000
OpenAlexW2561767092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.