Evidence map›Paper›PMID 28039105›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2017

Long-acting β

Mohammed O Altonsy, Mahmoud M Mostafa, Anthony N Gerber, Robert Newton

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Long-ActingMolecular pharmacology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Mohammed O AltonsyDepartment of Cell Biology and Anatomy, Airway Inflammation Research Group, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.
Mahmoud M MostafaDepartment of Cell Biology and Anatomy, Airway Inflammation Research Group, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.
Anthony N GerberDepartment of Medicine, National Jewish Health, Denver, Colorado; and.
Robert NewtonDepartment of Cell Biology and Anatomy, Airway Inflammation Research Group, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada; rnewton@ucalgary.ca.ORCID http://orcid.org/0000-0002-4919-8498
University of Calgary · CANational Jewish Health · US

Funding

Role of Klf15 in airway smooth muscle and the response to glucocorticoidsR01HL109557 · NHLBI · NATIONAL JEWISH HEALTH · PI GERBER, ANTHONY N · 2012 to 2025
$7.2M
NHLBI NIH HHS R01 HL109557
6 · The paper itself

Abstract

Glucocorticoids, or corticosteroids, are effective treatments for many chronic inflammatory diseases, and in mild/moderate asthma, long-acting β

Indexed as

Adrenergic beta-2 Receptor AgonistsBase SequenceBinding SitesBudesonideCell LineChromatin ImmunoprecipitationFeedback, PhysiologicalFormoterol FumarateGene Expression RegulationGene SilencingGlucocorticoidsHumansI-kappa B KinaseModels, BiologicalNF-kappa BProtein BindingAdrenergic beta-2 Receptor AgonistsBudesonideFormoterol FumarateGlucocorticoidsI-kappa B KinaseNF-kappa BRELA protein, humanRNA, MessengerRNA Polymerase IIRNA, Small InterferingTNFAIP3 protein, humanTranscription Factor RelATumor Necrosis Factor-alphaTumor Necrosis Factor alpha-Induced Protein 3chromatin immunoprecipitation (ChIP)glucocorticoid receptorlong-acting β2-agonistNF-κB (RELA)TNFα-induced protein-3

Identifiers

PMID28039105
PMCPMC8526330
OpenAlexW2564530684

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.