Evidence map›Paper›PMID 28036030›Full record

ArticleMolecules (Basel, Switzerland)2016

Xanthohumol, a Prenylated Chalcone from Hops, Inhibits the Viability and Stemness of Doxorubicin-Resistant MCF-7/ADR Cells.

Ming Liu, Hua Yin, Xiaokun Qian, Jianjun Dong, Zhonghua Qian, Jinlai Miao

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Acridine-Based Chalcone 1C and ABC Transporters.International journal of molecular sciences · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. A Novel Tri-Hydroxy-Methylated Chalcone Isolated fromInternational journal of molecular sciences · 2023
    Article
  13. Anticancer Potential of Natural Chalcones: In Vitro and In Vivo Evidence.International journal of molecular sciences · 2023
    Review
  14. Review
  15. Two Important Anticancer Mechanisms of Natural and Synthetic Chalcones.International journal of molecular sciences · 2022
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ming LiuKey Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China. lmouc@hotmail.com.
Hua YinState Key Laboratory of Biological Fermentation Engineering of Beer (In Preparation), Qingdao 266061, China. yinhua@tsingtao.com.cn.
Xiaokun QianCollege of Food Science and Engineering, Jiangxi Agricultural University, Nanchang 330045, China. azrsqxk97@163.com.
Jianjun DongState Key Laboratory of Biological Fermentation Engineering of Beer (In Preparation), Qingdao 266061, China. 15133634098@163.com.
Zhonghua QianState Key Laboratory of Biological Fermentation Engineering of Beer (In Preparation), Qingdao 266061, China. qianzh@tsingtao.com.cn.
Jinlai MiaoState Key Laboratory of Biological Fermentation Engineering of Beer (In Preparation), Qingdao 266061, China. miaojinlai@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xanthohumol is a unique prenylated flavonoid in hops (

Indexed as

Antibiotics, AntineoplasticApoptosisBiomarkers, TumorBreast NeoplasmsCell Cycle CheckpointsCell MovementCell SurvivalChalconeDoxorubicinDrug Resistance, NeoplasmFlavonoidsHumansHumulusMCF-7 CellsNeoplastic Stem CellsPropiophenonesAntibiotics, AntineoplasticBiomarkers, TumorChalconeDoxorubicinFlavonoidsPropiophenonesxanthohumoldoxorubicin resistancestemnessviabilityxanthohumol

Identifiers

PMID28036030
PMCPMC6155764

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.