Evidence map›Paper›PMID 28035625›Full record

ArticleMetabolic brain disease2017

Effect of dexmedetomidine on cerebral ischemia-reperfusion rats by activating mitochondrial ATP-sensitive potassium channel.

Feng Yuan, Hongguang Fu, Kai Sun, Shubiao Wu, Tieli Dong

Abstract read
PubMed Publisher
In one paragraph

Article in Metabolic brain disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Appraisal of the Neuroprotective Effect of Dexmedetomidine: A Meta-Analysis.Advances in experimental medicine and biology · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Feng YuanDepartment of Anesthesiology, The Second Affiliated Hospital of Zhengzhou University, No. 2 of Jingba road of Jinshui District, Zhengzhou, 450014, China.
Hongguang FuDepartment of Anesthesiology, The Second Affiliated Hospital of Zhengzhou University, No. 2 of Jingba road of Jinshui District, Zhengzhou, 450014, China.
Kai SunDepartment of Anesthesiology, The Second Affiliated Hospital of Zhengzhou University, No. 2 of Jingba road of Jinshui District, Zhengzhou, 450014, China.
Shubiao WuDepartment of Anesthesiology, The Second Affiliated Hospital of Zhengzhou University, No. 2 of Jingba road of Jinshui District, Zhengzhou, 450014, China.
Tieli DongDepartment of Anesthesiology, The Second Affiliated Hospital of Zhengzhou University, No. 2 of Jingba road of Jinshui District, Zhengzhou, 450014, China. 455275093@qq.com.ORCID 0000-0002-2494-1302
Second Affiliated Hospital of Zhengzhou University · CNZhengzhou Jinshui District General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study reported here was to evaluate whether the mitochondrial ATP-sensitive potassium (mitoK

Indexed as

Adrenergic alpha-AgonistsAnimalsAntioxidantsBrain ChemistryCytokinesDecanoic AcidsDexmedetomidineHydroxy AcidsKATP ChannelsMaleMiddle Cerebral ArteryMitochondriaNervous System DiseasesOxidative StressRatsRats, Sprague-Dawley5-hydroxydecanoic acidAdrenergic alpha-AgonistsAntioxidantsCytokinesDecanoic AcidsDexmedetomidineHydroxy AcidsKATP ChannelsAnti-inflammatory reactionAnti-oxidative stress reactionCerebral ischemia-reperfusionDexmedetomidineMitochondrial ATP-sensitive potassium channel

Identifiers

PMID28035625
OpenAlexW2565431706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.