ArticleInternational urology and nephrology2017
Community-acquired hypokalemia in elderly patients: related factors and clinical outcomes.
Article in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
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11 citing papers in PubMed, 22 citations in OpenAlex.
- Age-stratified efficacy and safety of esaxerenone versus angiotensin II receptor blockers in older patients with hypertension: a predefined subanalysis of the ESCORT-HT study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- The role of electrolytes imbalance in determining poor health outcomes in a cohort of older in-patients: the ELECTROHEALTH study.Aging clinical and experimental research · 2026Article
- Prediction of Postoperative Hypokalemia in Patients with Severe Carotid Artery Stenosis undergoing Standard Carotid Endarterectomy: A Retrospective Cohort Study.Annals of geriatric medicine and research · 2026Article
- The Influence of Hyponatremia and Hypokalemia on the Risk of Fractures in Various Anatomical Regions among Adult Trauma Patients: A Propensity Score-Matched Analysis.Diagnostics (Basel, Switzerland) · 2024Article
- Article
- [Application Value of Random Urine Potassium-to-Creatinine Ratio in Diagnosing Renal Potassium Loss].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023Article
- [Intraoperative management of potentially fatal arrhythmias after anesthesia induced by severe hypokalemia: A case report].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Association between preoperative hypokalemia and postoperative complications in elderly patients: a retrospective study.BMC geriatrics · 2022Article
- Unexpected clinical outcomes following the implementation of a standardised order set for hepatic encephalopathy.BMJ open gastroenterology · 2021Article
- Astragalus membranaceus and Punica granatum alleviate infertility and kidney dysfunction induced by aging in male rats.Turkish journal of biology = Turk biyoloji dergisi · 2020Article
- Drug-physiology interaction and its influence on the QT prolongation-mechanistic modeling study.Journal of pharmacokinetics and pharmacodynamics · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeElectrolyte imbalance is a common problem affecting the elderly. Increased number of comorbidities and frequent use of drugs may contribute to increased risk of hypokalemia in the elderly. This study was performed to investigate the prevalence of community-acquired hypokalemia (CAH), risk factors for its development, related factors with hypokalemia, and morbidities and all-cause mortality rates (MR) of CAH in the elderly patients.
methodsTotal of 36,361 patients aged above 65 years were screened retrospectively. Group 1 consisted of 269 elderly patients with potassium level ≤3.5 mmol/L, and group 2 (control group) consisted of 182 subjects with potassium level between 3.6 and 5.5 mmol/L. Etiologic factors of CAH, presence of comorbidities, duration of hospital stay, hospital cost, and clinical outcomes were recorded.
resultsPrevalence of hypokalemia was found 3.24% in patients aged above 65 years. Duration of hospital stay, presence of ≥2 comorbid diseases, hospital cost, and MR were significantly higher in group 1 compared to group 2 (p < 0.001 for all). Loop diuretics, hydrochlorothiazides, beta agonists, inadequate oral intake, and female gender were all independent risk factors for CAH in elderly patients. Patients with ≥2 comorbid diseases were found to have greater risk of hypokalemia than the patients with <2 comorbidities.
conclusionsLength of hospital stay, hospital cost, and MR were higher in elderly with CAH. Female gender, hydrochlorothiazides, loop diuretics, and ≥2 comorbid diseases are the leading risk factors associated with CAH in elderly.
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