Evidence map›Paper›PMID 28035496›Full record

ArticleAIDS and behavior2017

The Role of Current and Historical Alcohol Use in Hepatic Fibrosis Among HIV-Infected Individuals.

H Nina Kim, Heidi M Crane, Carla V Rodriguez, Stephen Van Rompaey, Kenneth H Mayer, Katerina Christopoulos, Sonia Napravnik, Geetanjali Chander, Heidi Hutton, Mary E McCaul and 8 more

Abstract read
In one paragraph

Article in AIDS and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Impact of Socio-Economic, Behavioural and Clinical Factors on Liver Disease Progression in Individuals With HIV and Hepatitis B.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Observational
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

H Nina KimDivision of Allergy and Infectious Diseases, Department of Medicine, School of Medicine, University of Washington, 325 Ninth Avenue, Box 359930, Seattle, WA, 98104, USA. hyangkim@uw.edu.
Heidi M CraneDivision of Allergy and Infectious Diseases, Department of Medicine, School of Medicine, University of Washington, 325 Ninth Avenue, Box 359930, Seattle, WA, 98104, USA.
Carla V RodriguezDivision of Allergy and Infectious Diseases, Department of Medicine, School of Medicine, University of Washington, 325 Ninth Avenue, Box 359930, Seattle, WA, 98104, USA.
Stephen Van RompaeyDivision of Allergy and Infectious Diseases, Department of Medicine, School of Medicine, University of Washington, 325 Ninth Avenue, Box 359930, Seattle, WA, 98104, USA.
Kenneth H MayerFenway Institute, Fenway Health, Boston, MA, USA.
Katerina ChristopoulosSchool of Medicine, University of California San Francisco, San Francisco, CA, USA.
Sonia NapravnikInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Geetanjali ChanderDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Heidi HuttonDepartment of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mary E McCaulDepartment of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Edward R CachayDepartment of Medicine, University of California San Diego, San Diego, CA, USA.
Michael J MugaveroDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AB, USA.
Richard MooreDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Elvin GengSchool of Medicine, University of California San Francisco, San Francisco, CA, USA.
Joseph J EronInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Michael S SaagDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AB, USA.
Joseph O MerrillDivision of Allergy and Infectious Diseases, Department of Medicine, School of Medicine, University of Washington, 325 Ninth Avenue, Box 359930, Seattle, WA, 98104, USA.
Mari M KitahataDivision of Allergy and Infectious Diseases, Department of Medicine, School of Medicine, University of Washington, 325 Ninth Avenue, Box 359930, Seattle, WA, 98104, USA. kitahata@uw.edu.
University of Washington · USJohns Hopkins University · USUniversity of Alabama at Birmingham · USUniversity of California, San Francisco · USUniversity of North Carolina at Chapel Hill · USFenway Health · USJohns Hopkins Medicine · USUniversity of California, San Diego · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
Unsolicited R24 for the CFAR-Network of Integrated Clinical Sciences, CNICSR24AI067039 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael S. Saag · 2006 to 2026
$99.4M
The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI OLAF KUTSCH · 1988 to 2026
$84.1M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
3/4 Alcohol Research Consortium in HIV - Epidemiological Research Arm (ARCH-ERA)U01AA020793 · NIAAA · UNIVERSITY OF WASHINGTON · PI CRANE, HEIDI M., LAU, BRYAN · 2011 to 2020
$5.8M
Integration of Evidence-based Alcohol Interventions into HIV CareU01AA020802 · NIAAA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CROPSEY, KAREN L, MUGAVERO, MICHAEL J · 2011 to 2020
$4.2M
1/4 Alcohol Research Consortium in HIV-Administrative Core (ARCH-AC)U24AA020801 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI CHANDER, GEETANJALI, MCCAUL, MARY E · 2011 to 2021
$3.5M
NIAAA NIH HHS U01 AA020793NIAAA NIH HHS U01 AA020802NIAAA NIH HHS U24 AA020801NIAID NIH HHS P30 AI027757NIAID NIH HHS P30 AI027763NIAID NIH HHS P30 AI027767NIAID NIH HHS P30 AI036214NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI060354NIAID NIH HHS P30 AI094189NIAID NIH HHS R24 AI067039
6 · The paper itself

Abstract

We examined risk factors for advanced hepatic fibrosis [fibrosis-4 (FIB)-4 >3.25] including both current alcohol use and a diagnosis of alcohol use disorder among HIV-infected patients. Of the 12,849 patients in our study, 2133 (17%) reported current hazardous drinking by AUDIT-C, 2321 (18%) had a diagnosis of alcohol use disorder, 2376 (18%) were co-infected with chronic hepatitis C virus (HCV); 596 (5%) had high FIB-4 scores >3.25 as did 364 (15%) of HIV/HCV coinfected patients. In multivariable analysis, HCV (adjusted odds ratio (aOR) 6.3, 95% confidence interval (CI) 5.2-7.5), chronic hepatitis B (aOR 2.0, 95% CI 1.5-2.8), diabetes (aOR 2.3, 95% CI 1.8-2.9), current CD4 <200 cells/mm

Indexed as

AdultAlcohol DrinkingAlcoholismCD4 Lymphocyte CountCoinfectionDiabetes MellitusFemaleHepatitis B, ChronicHepatitis C, ChronicHIV InfectionsHumansLiver CirrhosisMaleMiddle AgedOdds RatioRisk FactorsAlcoholCNICSHIVLiver fibrosis

Identifiers

PMID28035496
PMCPMC6029880
OpenAlexW2565272509

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.