Evidence map›Paper›PMID 28035332›Full record

ArticleMolecular therapy oncolytics2016

Poly-functional and long-lasting anticancer immune response elicited by a safe attenuated

Xavier Chauchet, Dalil Hannani, Sophia Djebali, David Laurin, Benoit Polack, Jacqueline Marvel, Laurent Buffat, Bertrand Toussaint, Audrey Le Gouëllec

Abstract read
In one paragraph

Article in Molecular therapy oncolytics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Engineering a dual vaccine against COVID-19 and tuberculosis.Frontiers in cellular and infection microbiology · 2023
    Article
  3. Frontiers in oncology · 2022
    Review
  4. Article
  5. EdibleNutrients · 2020
    Article
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xavier ChauchetLaboratoire TIMC-TheREx UMR 5525 CNRS-Université Grenoble Alpes, La Tronche, France; APCure SAS, Lyon, France.
Dalil HannaniAPCure SAS , Lyon, France.
Sophia DjebaliCIRI, Centre International de Recherche en Infectiologie, INSERM , Lyon, France.
David LaurinLaboratoire TIMC-TheREx UMR 5525 CNRS-Université Grenoble Alpes, La Tronche, France; Établissement Français du Sang, La Tronche, France.
Benoit PolackLaboratoire TIMC-TheREx UMR 5525 CNRS-Université Grenoble Alpes, La Tronche, France; Département d'Hématologie Oncologie Génétique et Immunologie, Institut de Biologie et Pathologie, C.H.U. de Grenoble,Grenoble, France.
Jacqueline MarvelCIRI, Centre International de Recherche en Infectiologie, INSERM , Lyon, France.
Laurent BuffatAPCure SAS , Lyon, France.
Bertrand ToussaintLaboratoire TIMC-TheREx UMR 5525 CNRS-Université Grenoble Alpes, La Tronche, France; Département de Biochimie Toxicologie Pharmacologie, UM Biochimie des Enzymes et des Protéines, Institut de Biologie et Pathologie, C.H.U. de Grenoble, Grenoble, France.
Audrey Le GouëllecLaboratoire TIMC-TheREx UMR 5525 CNRS-Université Grenoble Alpes, La Tronche, France; Département de Biochimie Toxicologie Pharmacologie, UM Biochimie des Enzymes et des Protéines, Institut de Biologie et Pathologie, C.H.U. de Grenoble, Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Live-attenuated bacterial vectors for antigens delivery have aroused growing interest in the field of cancer immunotherapy. Their potency to stimulate innate immunity and to promote intracellular antigen delivery into antigen-presenting cells could be exploited to elicit a strong and specific cellular immune response against tumor cells. We previously described genetically-modified and attenuated

Identifiers

PMID28035332
PMCPMC5155632

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.