ArticleWorld journal of gastrointestinal oncology2016
Signet ring colorectal carcinoma: Do we need to improve the treatment algorithm?
Article in World journal of gastrointestinal oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- A Case Illustrating Challenges: Early-Onset Signet Ring Cell Rectal Carcinoma With Fulminant Peritoneal Progression.Clinical case reports · 2026Article
- Article
- Case report: Coexistence of rectal signet ring cell carcinoma with neuroendocrine components.BMC geriatrics · 2025Article
- Systematic review of risk factors, prognosis, and management of colorectal signet-ring cell carcinoma.World journal of gastrointestinal oncology · 2024Article
- Total Neoadjuvant Therapy (TNT) with Full Dose Concurrent Chemotherapy in Locally Advanced Rectal Adenocarcinoma Including Signet Ring and Mucinous Cancers.Journal of gastrointestinal cancer · 2024Article
- Outcomes of rectal cancer patients with a positive pathological circumferential resection margin.Langenbeck's archives of surgery · 2022Article
- An Extremely Rare Case of Rectal Signet Ring Cell Carcinoma.Gastroenterology research · 2022Article
- MRI features of signet ring rectal cancer.Abdominal radiology (New York) · 2021Article
- Prognostic Significance of EMVI in Rectal Cancer in a Tertiary Cancer Hospital in India.The Indian journal of radiology & imaging · 2021Article
- Outcomes of Definitive Treatment of Signet Ring Cell Carcinoma of the Rectum: Is Minimal Invasive Surgery Detrimental in Signet Ring Rectal Cancers?Indian journal of surgical oncology · 2020Article
- Trends of incidence and survival in patients with gastroenteropancreatic signet ring cell carcinoma: an analysis from the Surveillance, Epidemiology, and End Results program.Journal of gastrointestinal oncology · 2019Article
- Clinical Utility of Staging Laparoscopy for Advanced Obstructing Rectal Adenocarcinoma: Emerging Tool.Indian journal of surgical oncology · 2018Article
- Demographic and Clinicopathological Patterns of Colorectal Cancer at the National Cancer Institute, Sudan.Saudi journal of medicine & medical sciencesArticle
- Adjuvant chemotherapy in stage II-III operated colon cancer patients from a nontrial cohort in a low colon cancer prevalence country with predominant use of modified CAPOX.South Asian journal of cancerArticle
- Practice patterns and outcomes with the use of regorafenib in metastatic colorectal cancer: Results from the Regorafenib in Metastatic colorectal cancer - An Indian exploratory analysis study.South Asian journal of cancerArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo elaborate about this peculiar variant from a tertiary cancer center from India.
methodsIt's a retrospective study (2011-2014) of all patients diagnosed with signet ring colo-rectal cancer (SRCC). Various clinico-pathological variables were studied.
resultsOne hundred and seventy consecutive patients with SRCC were diagnosed (11.4% of all colorectal cancers). Median Age of the cohort was 41 years. Most common location was recto-sigmoid area (54.7%). Majority patients presented in stage III and IV (91.2%). Most of the stage IV patients had isolated peritoneal metastases (86.5%). Colonic tumors had higher incidence of peritoneal metastases (91.8%
conclusionSRCC has predilection for peritoneal dissemination. More aggressive and/or extended chemotherapy schedules as well as prophylactic hyperthermic intra-peritoneal chemotherapy at the time of primary surgery may be attempted in these patients.
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