Evidence map›Paper›PMID 28035232›Full record

ReviewEvolutionary applications2017

Back into the wild-Apply untapped genetic diversity of wild relatives for crop improvement.

Hengyou Zhang, Neha Mittal, Larry J Leamy, Oz Barazani, Bao-Hua Song

Abstract readReview
In one paragraph

Review in Evolutionary applications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 158 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
158citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

158 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Role of the Genetic Background in Resistance to Plant Viruses.International journal of molecular sciences · 2018
    Pooled it
  2. Standardized microhaplotype databases and frameworks for assessing and mining crop genetic diversity.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Two Species of Wild Long-Fruited Jute (International journal of molecular sciences · 2026
    Article
  7. Article
  8. Article
  9. QTL-Seq and pyramiding of yield-related loci from wild rice (Molecular breeding : new strategies in plant improvement · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
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  19. Article
  20. Insights Into the Almond Domestication History.Evolutionary applications · 2025
    Article

98 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hengyou ZhangDepartment of Biological Sciences University of North Carolina at Charlotte Charlotte NC USA.
Neha MittalDepartment of Biological Sciences University of North Carolina at Charlotte Charlotte NC USA.
Larry J LeamyDepartment of Biological Sciences University of North Carolina at Charlotte Charlotte NC USA.
Oz BarazaniThe Institute for Plant Sciences Israel Plant Gene Bank Agricultural Research Organization Bet Dagan Israel.
Bao-Hua SongDepartment of Biological Sciences University of North Carolina at Charlotte Charlotte NC USA.

Funding

Molecular basis and evolution of complex trait variation with significance in human healthR15GM122029 · NIGMS · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI SONG, BAO-HUA · 2016 to 2016
$439k
NIGMS NIH HHS R15 GM122029
6 · The paper itself

Abstract

Deleterious effects of climate change and human activities, as well as diverse environmental stresses, present critical challenges to food production and the maintenance of natural diversity. These challenges may be met by the development of novel crop varieties with increased biotic or abiotic resistance that enables them to thrive in marginal lands. However, considering the diverse interactions between crops and environmental factors, it is surprising that evolutionary principles have been underexploited in addressing these food and environmental challenges. Compared with domesticated cultivars, crop wild relatives (CWRs) have been challenged in natural environments for thousands of years and maintain a much higher level of genetic diversity. In this review, we highlight the significance of CWRs for crop improvement by providing examples of CWRs that have been used to increase biotic and abiotic stress resistance/tolerance and overall yield in various crop species. We also discuss the surge of advanced biotechnologies, such as next-generation sequencing technologies and omics, with particular emphasis on how they have facilitated gene discovery in CWRs. We end the review by discussing the available resources and conservation of CWRs, including the urgent need for CWR prioritization and collection to ensure continuous crop improvement for food sustainability.

Indexed as

advanced biotechnologyclimate changeconservationcrop wild relativesenvironmental stressesfood security

Identifiers

PMID28035232
PMCPMC5192947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.