Evidence map›Paper›PMID 28035016›Full record

Trial reportJournal of applied physiology (Bethesda, Md. : 1985)2017

Esmolol infusion versus propranolol infusion: effects on heart rate and blood pressure in healthy volunteers.

Matthew D Muller, Tariq Ali Ahmad, Alvaro F Vargas Pelaez, David N Proctor, Anthony S Bonavia, J Carter Luck, Stephan R Maman, Amanda J Ross, Urs A Leuenberger, Patrick M McQuillan

Open access · bronzeAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Matthew D MullerPenn State Heart and Vascular Institute, Penn State University College of Medicine, Hershey, Pennsylvania; mmuller1@hmc.psu.edu.ORCID http://orcid.org/0000-0002-7411-8816
Tariq Ali AhmadPenn State Heart and Vascular Institute, Penn State University College of Medicine, Hershey, Pennsylvania.
Alvaro F Vargas PelaezPenn State Heart and Vascular Institute, Penn State University College of Medicine, Hershey, Pennsylvania.
David N ProctorDepartment of Kinesiology, Noll Laboratory, The Pennsylvania State University, University Park, Pennsylvania.
Anthony S BonaviaDepartment of Anesthesiology and Perioperative Medicine, Penn State University College of Medicine, Hershey, Pennsylvania; and.
J Carter LuckPenn State Heart and Vascular Institute, Penn State University College of Medicine, Hershey, Pennsylvania.
Stephan R MamanPenn State Heart and Vascular Institute, Penn State University College of Medicine, Hershey, Pennsylvania.
Amanda J RossPenn State Heart and Vascular Institute, Penn State University College of Medicine, Hershey, Pennsylvania.
Urs A LeuenbergerPenn State Heart and Vascular Institute, Penn State University College of Medicine, Hershey, Pennsylvania.
Patrick M McQuillanDepartment of Anesthesiology and Perioperative Medicine, Penn State University College of Medicine, Hershey, Pennsylvania; and.
Penn State Milton S. Hershey Medical Center · USPennsylvania State University · USUniversity School · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
Penn State Institutional Career Development CoreKL2TR002015 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI VAN SCOY, LAUREN JODI · 2016 to 2025
$7.8M
Penn State Clinical and Translational Science InstituteKL2TR000126 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$3.2M
Intermittent Hypoxia: A Model to Study Circulatory Control in HumansR01HL098379 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LEUENBERGER, URS A · 2010 to 2012
$462k
NCATS NIH HHS KL2 TR000126NCATS NIH HHS KL2 TR002015NCATS NIH HHS UL1 TR000127NCATS NIH HHS UL1 TR002014NHLBI NIH HHS R01 HL098379
6 · The paper itself

Abstract

Despite its widespread clinical use, the β

Indexed as

AdultAnti-Arrhythmia AgentsBlood PressureExercise TestFemaleHeart RateHumansInfusions, IntravenousMaleMiddle AgedPropanolaminesPropranololReference ValuesTreatment OutcomeAnti-Arrhythmia AgentsesmololPropanolaminesPropranololblood pressureheart ratesympathetic nervous system

Identifiers

PMID28035016
PMCPMC5401955
OpenAlexW2561097661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.