Evidence map›Paper›PMID 28035001›Full record

ArticleThe Journal of biological chemistry2017

Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor.

Guiqing Peng, Yang Yang, Joseph R Pasquarella, Liqing Xu, Zhaohui Qian, Kathryn V Holmes, Fang Li

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Structural basis for mouse receptor recognition by bat SARS2-like coronaviruses.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Guiqing PengFrom the Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455.
Yang YangFrom the Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455.
Joseph R PasquarellaFrom the Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455.
Liqing XuFrom the Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455.
Zhaohui Qianthe MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China, and.
Kathryn V Holmesthe Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado 80045.
Fang LiFrom the Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, lifang@umn.edu.
University of Minnesota Medical Center · USChinese Academy of Medical Sciences & Peking Union Medical College · CNHuazhong Agricultural University · CNUniversity of Colorado Denver · US

Funding

Receptor recognition mechanisms of coronavirusesR01AI089728 · NIAID · UNIVERSITY OF MINNESOTA · PI Fang Li, Timothy Patrick Sheahan · 2010 to 2026
$4.7M
NIAID NIH HHS R01 AI089728
6 · The paper itself

Abstract

Hosts and pathogens are locked in an evolutionary arms race. To infect mice, mouse hepatitis coronavirus (MHV) has evolved to recognize mouse CEACAM1a (mCEACAM1a) as its receptor. To elude MHV infections, mice may have evolved a variant allele from the

Indexed as

Amino Acid SequenceAnimalsBinding SitesCarcinoembryonic AntigenCrystallography, X-RayMembrane FusionMiceMurine hepatitis virusMutationProtein ConformationReceptors, VirusSequence Homology, Amino AcidCarcinoembryonic AntigenCeacam1 protein, mouseReceptors, Virusevolutionreceptor structure-functionvirusvirus entryX-ray crystallography

Identifiers

PMID28035001
PMCPMC5313091
OpenAlexW2562227004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.