Evidence map›Paper›PMID 28034994›Full record

ArticleAJNR. American journal of neuroradiology2017

MR Fingerprinting of Adult Brain Tumors: Initial Experience.

C Badve, A Yu, S Dastmalchian, M Rogers, D Ma, Y Jiang, S Margevicius, S Pahwa, Z Lu, M Schluchter and 4 more

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. A MR Fingerprinting Development Kit for Quantitative 3D Brain Imaging.Journal of magnetic resonance imaging : JMRI · 2026
    Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Clinical MR Biomarkers.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  9. Time-resolved MR fingerprinting for TMagnetic resonance in medicine · 2025
    Article
  10. Radiomics in glioma: emerging trends and challenges.Annals of clinical and translational neurology · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

C BadveFrom the Department of Radiology (C.B., S.D., D.M., S.P., J.S., M.G., V.G.), University Hospitals Cleveland Medical Center and Case Western Reserve University, Cleveland, Ohio chaitra.badve@uhhospitals.org.ORCID 0000-0001-8547-8019
A YuSchool of Medicine (A.Y., M.R., Z.L.).ORCID 0000-0003-3422-4283
S DastmalchianFrom the Department of Radiology (C.B., S.D., D.M., S.P., J.S., M.G., V.G.), University Hospitals Cleveland Medical Center and Case Western Reserve University, Cleveland, Ohio.ORCID 0000-0003-0977-4080
M RogersSchool of Medicine (A.Y., M.R., Z.L.).ORCID 0000-0001-7886-2223
D MaFrom the Department of Radiology (C.B., S.D., D.M., S.P., J.S., M.G., V.G.), University Hospitals Cleveland Medical Center and Case Western Reserve University, Cleveland, Ohio.ORCID 0000-0003-1664-9579
Y JiangDepartment of Biomedical Engineering (Y.J., M.G., V.G.).ORCID 0000-0001-5010-2265
S MargeviciusDepartment of Epidemiology and Biostatistics (S.M., M.S.), Case Western Reserve University, Cleveland, Ohio.ORCID 0000-0001-5663-8319
S PahwaFrom the Department of Radiology (C.B., S.D., D.M., S.P., J.S., M.G., V.G.), University Hospitals Cleveland Medical Center and Case Western Reserve University, Cleveland, Ohio.ORCID 0000-0002-3219-874X
Z LuSchool of Medicine (A.Y., M.R., Z.L.).ORCID 0000-0002-0003-9189
M SchluchterDepartment of Epidemiology and Biostatistics (S.M., M.S.), Case Western Reserve University, Cleveland, Ohio.ORCID 0000-0001-7803-0670
J SunshineFrom the Department of Radiology (C.B., S.D., D.M., S.P., J.S., M.G., V.G.), University Hospitals Cleveland Medical Center and Case Western Reserve University, Cleveland, Ohio.ORCID 0000-0002-3227-8715
M GriswoldFrom the Department of Radiology (C.B., S.D., D.M., S.P., J.S., M.G., V.G.), University Hospitals Cleveland Medical Center and Case Western Reserve University, Cleveland, Ohio.ORCID 0000-0002-3011-6747
A SloanDepartments of Neurosurgery and Pathology (A.S.), University Hospitals-Cleveland Medical Center, Seidman Cancer Center and the Case Comprehensive Cancer Center, Cleveland, Ohio.ORCID 0000-0001-9607-5063
V GulaniFrom the Department of Radiology (C.B., S.D., D.M., S.P., J.S., M.G., V.G.), University Hospitals Cleveland Medical Center and Case Western Reserve University, Cleveland, Ohio.ORCID 0000-0003-0889-5999

Funding

Magnetic Resonance Fingerprinting (MRF) for Improved High Field MRR01EB017219 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI GRISWOLD, MARK · 2013 to 2016
$2.5M
Optimization of MR Fingerprinting (MRF) for Quantitative MRIR01EB016728 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI GRISWOLD, MARK, GULANI, VIKAS · 2014 to 2017
$2.0M
NIBIB NIH HHS R01 EB016728NIBIB NIH HHS R01 EB017219
6 · The paper itself

Abstract

background and purposeMR fingerprinting allows rapid simultaneous quantification of T1 and T2 relaxation times. This study assessed the utility of MR fingerprinting in differentiating common types of adult intra-axial brain tumors. MATERIALS AND

methodsMR fingerprinting acquisition was performed in 31 patients with untreated intra-axial brain tumors: 17 glioblastomas, 6 World Health Organization grade II lower grade gliomas, and 8 metastases. T1, T2 of the solid tumor, immediate peritumoral white matter, and contralateral white matter were summarized within each ROI. Statistical comparisons on mean, SD, skewness, and kurtosis were performed by using the univariate Wilcoxon rank sum test across various tumor types. Bonferroni correction was used to correct for multiple-comparison testing. Multivariable logistic regression analysis was performed for discrimination between glioblastomas and metastases, and area under the receiver operator curve was calculated.

resultsMean T2 values could differentiate solid tumor regions of lower grade gliomas from metastases (mean, 172 ± 53 ms, and 105 ± 27 ms, respectively;

conclusionsMR fingerprinting allows rapid simultaneous T1 and T2 measurement in brain tumors and surrounding tissues. MR fingerprinting-based relaxometry can identify quantitative differences between solid tumor regions of lower grade gliomas and metastases and between peritumoral regions of glioblastomas and lower grade gliomas.

Indexed as

AdultAgedBrain NeoplasmsDiffusion Magnetic Resonance ImagingFemaleHumansMaleMiddle AgedStatistics, Nonparametric

Identifiers

PMID28034994
PMCPMC5352493

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.