Evidence map›Paper›PMID 28034989›Full record

ArticleHaematologica2017

Serum B-cell maturation antigen: a novel biomarker to predict outcomes for multiple myeloma patients.

Michael Ghermezi, Mingjie Li, Suzie Vardanyan, Nika Manik Harutyunyan, Jillian Gottlieb, Ariana Berenson, Tanya M Spektor, Claudia Andreu-Vieyra, Sophia Petraki, Eric Sanchez and 5 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 1 synthesis or guideline pooled it, 181 citations in OpenAlex.

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61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Michael GhermeziInstitute for Myeloma & Bone Cancer Research, West Hollywood, CA, USA.
Mingjie LiInstitute for Myeloma & Bone Cancer Research, West Hollywood, CA, USA.
Suzie VardanyanInstitute for Myeloma & Bone Cancer Research, West Hollywood, CA, USA.
Nika Manik HarutyunyanInstitute for Myeloma & Bone Cancer Research, West Hollywood, CA, USA.
Jillian GottliebInstitute for Myeloma & Bone Cancer Research, West Hollywood, CA, USA.
Ariana BerensonInstitute for Myeloma & Bone Cancer Research, West Hollywood, CA, USA.
Tanya M SpektorOncotherapeutics, West Hollywood, CA, USA.
Claudia Andreu-VieyraOncotherapeutics, West Hollywood, CA, USA.
Sophia PetrakiOncotherapeutics, West Hollywood, CA, USA.
Eric SanchezInstitute for Myeloma & Bone Cancer Research, West Hollywood, CA, USA.
Kyle UddInstitute for Myeloma & Bone Cancer Research, West Hollywood, CA, USA.
Cathy S WangInstitute for Myeloma & Bone Cancer Research, West Hollywood, CA, USA.
Regina A SwiftJames R. Berenson, MD, Inc., West Hollywood, CA, USA.
Haiming ChenInstitute for Myeloma & Bone Cancer Research, West Hollywood, CA, USA.
James R BerensonInstitute for Myeloma & Bone Cancer Research, West Hollywood, CA, USA jberenson@imbcr.org.
Institute for Myeloma & Bone Cancer Research · USOncotherapeutics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

B-cell maturation antigen is expressed on plasma cells. In this study, we have identified serum B-cell maturation antigen as a novel biomarker that can monitor and predict outcomes for multiple myeloma patients. Compared to healthy donors, patients with multiple myeloma showed elevated serum B-cell maturation antigen levels (

Indexed as

Biomarkers, TumorAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsB-Cell Maturation AntigenBiomarkersBone MarrowFemaleHumansMaleMiddle AgedMultiple MyelomaNeoplasm StagingPlasma CellsPrognosisB-Cell Maturation AntigenBiomarkersBiomarkers, Tumor

Identifiers

PMID28034989
PMCPMC5395119
OpenAlexW2562243521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.