Evidence map›Paper›PMID 28034985›Full record

Trial reportPain medicine (Malden, Mass.)2017

Psychosocial Influences on Exercise-Induced Hypoalgesia.

Angelique G Brellenthin, Kevin M Crombie, Dane B Cook, Nalini Sehgal, Kelli F Koltyn

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pain medicine (Malden, Mass.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angelique G BrellenthinDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Kevin M CrombieDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Dane B CookDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Nalini SehgalRehabilitation Medicine, University of Wisconsin-Madison, Wisconsin, USA.
Kelli F KoltynDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Funding

INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
Attenuation of Pain in Men and Women: Mechanisms of Exercise-Induced AnalgesiaR21AR057159 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI KOLTYN, KELLI F · 2010 to 2011
$321k
NCRR NIH HHS UL1 RR025011NIAMS NIH HHS R21 AR057159
6 · The paper itself

Abstract

Objective: The purpose of this study was to examine psychosocial influences on exercise-induced hypoalgesia (EIH). Design: Randomized controlled trial. Setting: Clinical research unit in a hospital. Subjects: Fifty-eight healthy men and women (mean age = 21 ± 3 years) participated in this study. Methods: Participants were first asked to complete a series of baseline demographic and psychological questionnaires including the Pain Catastrophizing Scale, the Fear of Pain Questionnaire, and the Family Environment Scale. Following this, they were familiarized with both temporal summation of heat pain and pressure pain testing protocols. During their next session, participants completed the Profile of Mood States, rated the intensity of heat pulses, and indicated their pressure pain thresholds and ratings before and after three minutes of submaximal, isometric exercise. Situational catastrophizing was assessed at the end of the experimental session. Results: Results indicated that experimental pain sensitivity was significantly reduced after exercise ( P  < 0.05). Men and women did not differ on any of the measured psychosocial variables ( P  > 0.05). Positive family environments predicted attenuated pain sensitivity and greater EIH, whereas negative and chronic pain-present family environments predicted worse pain and EIH outcomes. Situational catastrophizing and negative mood state also predicted worse pain and EIH outcomes and were additionally associated with increased ratings of perceived exertion and muscle pain during exercise. Conclusions: This study provides preliminary evidence that psychosocial variables, such as the family environment and mood states, can affect both pain sensitivity and the ability to modulate pain through exercise-induced hypoalgesia.

Indexed as

ExerciseFemaleHumansMaleNaltrexoneNarcotic AntagonistsPainPain ThresholdPsychologyYoung AdultNaltrexoneNarcotic AntagonistsCatastrophizingExerciseFamilyModulationPsychologicalSex

Identifiers

PMID28034985
PMCPMC8491610

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.