Evidence map›Paper›PMID 28034646›Full record

ArticleBioorganic & medicinal chemistry2017

2-Oxoamides based on dipeptides as selective calcium-independent phospholipase A

Anneta Smyrniotou, Maroula G Kokotou, Varnavas D Mouchlis, Efrosini Barbayianni, George Kokotos, Edward A Dennis, Violetta Constantinou-Kokotou

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioorganic & medicinal chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Small-molecule inhibitors as potential therapeutics and as tools to understand the role of phospholipases ABiochimica et biophysica acta. Molecular and cell biology of lipids · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Anneta SmyrniotouChemical Laboratories, Agricultural University of Athens, Iera Odos 75, Athens 11855, Greece.
Maroula G KokotouLaboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Athens 15771, Greece; Department of Pharmacology and Department of Chemistry and Biochemistry, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0601, USA.
Varnavas D MouchlisDepartment of Pharmacology and Department of Chemistry and Biochemistry, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0601, USA.
Efrosini BarbayianniLaboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Athens 15771, Greece.
George KokotosLaboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Athens 15771, Greece.
Edward A DennisDepartment of Pharmacology and Department of Chemistry and Biochemistry, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0601, USA. Electronic address: edennis@ucsd.edu.
Violetta Constantinou-KokotouChemical Laboratories, Agricultural University of Athens, Iera Odos 75, Athens 11855, Greece. Electronic address: vikon@aua.gr.
National and Kapodistrian University of Athens · GRAgricultural University of Athens · GRUniversity of California, San Diego · US

Funding

ACTION OF LIPOLYTIC ENZYMESR01GM020501 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DENNIS, EDWARD A · 1985 to 2020
$7.3M
NIGMS NIH HHS R01 GM020501
6 · The paper itself

Abstract

Calcium-independent phospholipase A

Indexed as

DipeptidesDose-Response Relationship, DrugHumansMolecular StructurePhospholipase A2 InhibitorsPhospholipases A2, Calcium-IndependentPyridinesStructure-Activity RelationshipDipeptidesoxoamidePhospholipase A2 InhibitorsPhospholipases A2, Calcium-IndependentPyridinesDipeptidesInhibitorsOxoamidesPhospholipase A(2)Pseudodipeptides

Identifiers

PMID28034646
PMCPMC5291822
OpenAlexW2560302595

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.