Evidence map›Paper›PMID 28034548›Full record

ReviewSeminars in fetal & neonatal medicine2017

Acute kidney injury in the fetus and neonate.

Arwa Nada, Elizabeth M Bonachea, David J Askenazi

Abstract readReview
In one paragraph

Review in Seminars in fetal & neonatal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. The Long-Term Effect of Preterm Birth on Renal Function: A Meta-Analysis.International journal of environmental research and public health · 2021
    Pooled it
  3. Review
  4. Article
  5. Article
  6. Neonatal acute kidney injury: where are we now?Pediatric nephrology (Berlin, Germany) · 2026
    Review
  7. Review
  8. Neonatal acute kidney injury: a survey of practices in Canadian neonatal intensive care units.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Proteinuria in preterm neonates: influence of fetal growth restriction.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Observational
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Arwa NadaDivision of Pediatric Nephrology, Faculty of Medicine, University of Alexandria, ElShatby, Alexandria, Egypt; Division of Pediatric Nephrology, The University of Tennessee Health Science Center, Le Bonheur Children's Hospital, 49 North Dunlap, Suite 326, Memphis, TN 38105, USA.
Elizabeth M BonacheaDepartment of Pediatrics, The Ohio State University, Section of Neonatology, Nationwide Children's Hospital, Columbus, OH, USA.
David J AskenaziDepartment of Pediatrics, Division of Pediatric Nephrology, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: daskenazi@peds.uab.edu.

Funding

UAB Center for Clinical and Translational Science (CCTS)UL1TR001417 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2015 to 2018
$31.4M
UAB Center for Clinical and Translational Science (CCTS) UL1UL1TR000165 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2012 to 2013
$9.6M
Recombinant Erythropoietin for Protection of Infant Renal Disease(REPAIReD)R01DK103608 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI ASKENAZI, DAVID JOSEPH, GOLDSTEIN, STUART L · 2014 to 2019
$3.0M
UAB Center for Clinical and Translational Science (CCTS) T32 (TL1)TL1TR000167 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2012 to 2013
$111k
NCATS NIH HHS TL1 TR000167NCATS NIH HHS UL1 TR000165NCATS NIH HHS UL1 TR001417NIDDK NIH HHS R01 DK103608
6 · The paper itself

Abstract

Acute kidney injury (AKI) is an under-recognized morbidity of neonates; the incidence remains unclear due to the absence of a unified definition of AKI in this population and because previous studies have varied greatly in screening for AKI with serum creatinine and urine output assessments. Premature infants may be born with less than half of the nephrons compared with term neonates, predisposing them to chronic kidney disease (CKD) early on in life and as they age. AKI can also lead to CKD, and premature infants with AKI may be at very high risk for long-term kidney problems. AKI in neonates is often multifactorial and may result from prenatal, perinatal, or postnatal insults as well as any combination thereof. This review focuses on the causes of AKI, the importance of early detection, the management of AKI in neonates, and long-term sequela of AKI in neonates.

Indexed as

Acute Kidney InjuryEarly DiagnosisHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesKidneyKidney Function TestsRenal Replacement TherapyAcute kidney injuryKidney adaptationNeonateRenal replacement therapy

Identifiers

PMID28034548
PMCPMC5373985

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.