Evidence map›Paper›PMID 28033038›Full record

ArticleNucleus (Austin, Tex.)2017

MGO3 and GIP1 act synergistically for the maintenance of centromeric cohesion.

Morgane Batzenschlager, Anne-Catherine Schmit, Etienne Herzog, Joerg Fuchs, Veit Schubert, Guy Houlné, Marie-Edith Chabouté

Open access · goldAbstract read
In one paragraph

Article in Nucleus (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Morgane Batzenschlagera Institut de Biologie Moléculaire des Plantes, CNRS , Université de Strasbourg , Strasbourg , France.
Anne-Catherine Schmita Institut de Biologie Moléculaire des Plantes, CNRS , Université de Strasbourg , Strasbourg , France.
Etienne Herzoga Institut de Biologie Moléculaire des Plantes, CNRS , Université de Strasbourg , Strasbourg , France.
Joerg Fuchsb Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben , Stadt Seeland , Germany.
Veit Schubertb Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben , Stadt Seeland , Germany.
Guy Houlnéa Institut de Biologie Moléculaire des Plantes, CNRS , Université de Strasbourg , Strasbourg , France.
Marie-Edith Chaboutéa Institut de Biologie Moléculaire des Plantes, CNRS , Université de Strasbourg , Strasbourg , France.
Université de Strasbourg · FRCentre National de la Recherche Scientifique · FRLeibniz Institute of Plant Genetics and Crop Plant Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The control of genomic maintenance during S phase is crucial in eukaryotes. It involves the establishment of sister chromatid cohesion, ensuring faithful chromosome segregation, as well as proper DNA replication and repair to preserve genetic information. In animals, nuclear periphery proteins - including inner nuclear membrane proteins and nuclear pore-associated components - are key factors which regulate DNA integrity. Corresponding functional homologues are not so well known in plants which may have developed specific mechanisms due to their sessile life. We have already characterized the Gamma-tubulin Complex Protein 3-interacting proteins (GIPs) as essential regulators of centromeric cohesion at the nuclear periphery. GIPs were also shown to interact with TSA1, first described as a partner of the epigenetic regulator MGOUN3 (MGO3)/BRUSHY1 (BRU1)/TONSOKU (TSK) involved in genomic maintenance. Here, using genetic analyses, we show that the mgo3gip1 mutants display an impaired and pleiotropic development including fasciation. We also provide evidence for the contribution of both MGO3 and GIP1 to the regulation of centromeric cohesion in Arabidopsis.

Indexed as

ArabidopsisArabidopsis ProteinsCarrier ProteinsCentromereChromatidsChromosomal Proteins, Non-HistoneDNA ReplicationMutationPhenotypeArabidopsis ProteinsAT3G18730 protein, ArabidopsisCarrier ProteinsChromosomal Proteins, Non-HistoneGIP1 protein, ArabidopsisArabidopsiscentromeric cohesionGIPMGO3nuclear envelope periphery

Identifiers

PMID28033038
PMCPMC5287105
OpenAlexW2279282337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.