Evidence map›Paper›PMID 28032758›Full record

ArticleThe Journal of organic chemistry2017

Synthesis and Electron Spin Relaxation of Tetracarboxylate Pyrroline Nitroxides.

Shengdian Huang, Joseph T Paletta, Hanan Elajaili, Kirby Huber, Maren Pink, Suchada Rajca, Gareth R Eaton, Sandra S Eaton, Andrzej Rajca

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Quantifying methyl tunneling induced (de)coherence of nitroxides in glassyPhysical chemistry chemical physics : PCCP · 2023
    Article
  4. Article
  5. Article
  6. Journal of magnetic resonance (San Diego, Calif. : 1997) · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. PEGylated, Water-Soluble, Stable Aminyl Radical.The Journal of organic chemistry · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shengdian HuangDepartment of Chemistry, University of Nebraska , Lincoln, Nebraska 68588-0304, United States.
Joseph T PalettaDepartment of Chemistry, University of Nebraska , Lincoln, Nebraska 68588-0304, United States.
Hanan ElajailiDepartment of Chemistry and Biochemistry, University of Denver , Denver, Colorado 80208-2436, United States.
Kirby HuberDepartment of Chemistry and Biochemistry, University of Denver , Denver, Colorado 80208-2436, United States.
Maren PinkIUMSC, Department of Chemistry, Indiana University , Bloomington, Indiana 47405-7102, United States.
Suchada RajcaDepartment of Chemistry, University of Nebraska , Lincoln, Nebraska 68588-0304, United States.
Gareth R EatonDepartment of Chemistry and Biochemistry, University of Denver , Denver, Colorado 80208-2436, United States.
Sandra S EatonDepartment of Chemistry and Biochemistry, University of Denver , Denver, Colorado 80208-2436, United States.
Andrzej RajcaDepartment of Chemistry, University of Nebraska , Lincoln, Nebraska 68588-0304, United States.ORCID 0000-0002-8856-1536

Funding

Synthetic Antigen Binder CoreU54GM087519 · NIGMS · UNIVERSITY OF CHICAGO · PI MCHAOURAB, HASSANE S · 2010 to 2017
$31.9M
New Nitroxide Spin Labels for Distance Measurements in Biological SystemsR01GM124310 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI RAJCA, ANDRZEJ · 2017 to 2020
$1.7M
Synthesis of Metal-Free Magnetic Resonance Imaging Contrast AgentsR01EB019950 · NIBIB · UNIVERSITY OF NEBRASKA LINCOLN · PI RAJCA, ANDRZEJ · 2015 to 2018
$1.2M
NIBIB NIH HHS R01 EB019950NIGMS NIH HHS R01 GM124310NIGMS NIH HHS U54 GM087519
6 · The paper itself

Abstract

We report the design, synthesis, and electron spin relaxation properties of hydrophilic tetracarboxylate ester pyrroline nitroxides 1 and 2, which serve as models in the search for new spin labels for DEER distance measurement at room temperature. The nitroxides are designed to have the methyl groups further away from the N-O spin site to decrease the inequivalent couplings of the unpaired electron to the methyl protons that shorten T

Indexed as

Carboxylic AcidsCrystallography, X-RayElectron Spin Resonance SpectroscopyModels, MolecularMolecular StructureNitrogen OxidesPyrrolesCarboxylic AcidsNitrogen OxidesPyrrolespyrroline

Identifiers

PMID28032758
PMCPMC5478179

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.