ArticleInternational journal of clinical practice2016
Relationship between age and erectile dysfunction diagnosis or treatment using real-world observational data in the USA.
Article in International journal of clinical practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- Non-linear relationships between inflammatory indices and erectile dysfunction in a group of young men living with HIV.Basic and clinical andrology · 2026Article
- Sexual functioning after the age of 40 in adults with moderate or severe congenital heart disease.International journal of cardiology. Congenital heart disease · 2026Article
- A population-based survey of self-reported and IIEF-defined erectile dysfunction among adult men in the United States in 2021.BMC public health · 2025Article
- Impact of Obesity, Smoking, and Alcohol on Erectile Dysfunction: A Cross-Sectional Study of Lebanese Men.Cureus · 2025Article
- Article
- The impact of PDE5 inhibitors on cardiovascular outcomes.Global cardiology science & practice · 2025Review
- Prevalence and treatment patterns of erectile dysfunction and hypogonadism in men with spina bifida: a retrospective study.Frontiers in urology · 2025Article
- From Oral to Sublingual: A Redefined Avanafil Tablet with a Breakthrough in Bioavailability and First-Pass Metabolism Avoidance.Drug design, development and therapy · 2025Article
- Is low-intensity shockwave therapy for erectile dysfunction a durable treatment option?-long-term outcomes of a randomized sham-controlled trial.Translational andrology and urology · 2024Article
- Factors Associated with Erectile Dysfunction Among Older Gay Men.Archives of sexual behavior · 2024Article
- Interrogating erectile dysfunction and evaluating novel therapeutic frontiers, with emphasis on stem cell strategies.Journal of assisted reproduction and genetics · 2024Review
- Association of erectile dysfunction and peripheral arterial disease in NHANES 2001-2004: a cross-sectional study.Frontiers in endocrinology · 2024Article
- Characteristics of men who use direct-to-consumer men's health telemedicine services.International journal of impotence research · 2023Article
- Incorporating sodium deoxycholate endorsed the buccal administration of avanafil to heighten the bioavailability and duration of action.Drug delivery and translational research · 2023Article
- A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men.Journal of personalized medicine · 2023Article
- The 18-year risk of cancer, angioedema, insomnia, depression, and erectile dysfunction in association with antihypertensive drugs: post-trial analyses from ALLHAT-Medicare linked data.Frontiers in cardiovascular medicine · 2023Article
- Health-Care Resource Utilization and Treatment Patterns in Men with Erectile Dysfunction and Benign Prostatic Hyperplasia-Associated Lower Urinary Tract Symptoms in the United States: A Retrospective Database Study.Patient preference and adherence · 2023Article
- Relationship Between Age, Comorbidity, and the Prevalence of Erectile Dysfunction.European urology focus · 2023Article
- Sexual function and fertility of adult males with anorectal malformations or Hirschsprung disease.Pediatric surgery international · 2022Article
- Shock Wave Therapy for Erectile Dysfunction: Marketing and Practice Trends in Major Metropolitan Areas in the United States.Urology practice · 2022Article
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Funding
Abstract
aimsWith self-reporting of erectile dysfunction (ED) in population-based surveys, men with ED may not represent men who are bothered sufficiently to seek an ED diagnosis and treatment. We used real-world observational data to assess: 1) the prevalence of ED diagnosis or treatment by age subgroups; and 2) the relationship of age with ED diagnosis or treatment after controlling for ED-related comorbidities in the USA.
methodsThis cross-sectional study used de-identified claims data (MarketScan
resultsOf 19,833,939 men meeting inclusion criteria in the primary analysis, only 1 108 842 (5.6%) had an ED diagnosis or PDE5I prescription (mean [SD] age: 55.2 [11.2] years). Prevalence of ED diagnosis or treatment increased from age 18-29 years (0.4%) to 60-69 years (11.5%), then decreased in the seventh (11.0%), eighth (4.6%), and ninth (0.9%) decades. Men with ED diagnosis or treatment had a higher prevalence of any comorbidity (63.1% vs 29.3% for men without ED) and of each comorbid condition. In multivariate analyses, age was an independent risk factor for ED diagnosis or treatment. Sensitivity analysis provided consistent results.
conclusionsIn a real-world setting in the USA, the prevalence of ED diagnosis or PDE5I treatment is generally low, increases with age, decreases in very old men, and is associated with increased prevalence of comorbidities. Age is an independent risk factor for ED diagnosis or treatment after controlling for comorbidities.
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