Evidence map›Paper›PMID 28032254›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2018

White matter correlates of the disorganized speech dimension in schizophrenia.

Petra V Viher, Katharina Stegmayer, Stéphanie Giezendanner, Andrea Federspiel, Stephan Bohlhalter, Roland Wiest, Werner Strik, Sebastian Walther

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Article in European archives of psychiatry and clinical neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  5. Article
  6. Article
  7. Psychotropic drug-prescribing correlates of disorganized speech in Asians with schizophrenia: The REAP-AP study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Petra V ViherTranslational Research Center, University Hospital of Psychiatry, Bolligenstrasse 111, 3000, Bern 60, Switzerland. petra.viher@puk.unibe.ch.
Katharina StegmayerTranslational Research Center, University Hospital of Psychiatry, Bolligenstrasse 111, 3000, Bern 60, Switzerland.
Stéphanie GiezendannerTranslational Research Center, University Hospital of Psychiatry, Bolligenstrasse 111, 3000, Bern 60, Switzerland.
Andrea FederspielTranslational Research Center, University Hospital of Psychiatry, Bolligenstrasse 111, 3000, Bern 60, Switzerland.
Stephan BohlhalterDepartment of Clinical Research, Inselspital, Bern, Switzerland.
Roland WiestSupport Center of Advanced Neuroimaging (SCAN), University Institute of Diagnostic and Interventional Neuroradiology, Inselspital, Bern, Switzerland.
Werner StrikTranslational Research Center, University Hospital of Psychiatry, Bolligenstrasse 111, 3000, Bern 60, Switzerland.
Sebastian WaltherTranslational Research Center, University Hospital of Psychiatry, Bolligenstrasse 111, 3000, Bern 60, Switzerland.

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 152619/1
6 · The paper itself

Abstract

Disorganized speech is related to functional abnormalities in schizophrenia. To test the association between formal thought disorders (FTDs) and white matter microstructure, we applied a behavioral rating and diffusion tensor imaging in 61 patients with schizophrenia spectrum disorders. The Bern Psychopathology Scale was used to rate the dimension of language abnormalities ranging from negative FTDs, basically unaltered speech, to positive FTDs. Tract-based spatial statistics indicated increased fractional anisotropy in left hemispheric pathways of the language system in patients with negative FTDs. Thus, altered white matter properties in relevant fiber tracts may represent vulnerability to specific formal thought disorders.

Indexed as

Statistics as TopicAdultAnalysis of VarianceAnisotropyDiffusion Tensor ImagingFemaleFunctional LateralityHumansImage Processing, Computer-AssistedMaleMiddle AgedPsychiatric Status Rating ScalesSchizophreniaSpeech DisordersWhite MatterBern Psychopathology ScaleDiffusion tensor imagingFormal thought disordersLanguage systemTract-based spatial statistics

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.