Evidence map›Paper›PMID 28032249›Full record

Trial reportNeurocritical care2017

Anxiety and Depressive Symptoms Among Two Seriously Medically Ill Populations and Their Family Caregivers: A Comparison and Clinical Implications.

Kelly M Shaffer, Jamie M Jacobs, Jessica N Coleman, Jennifer S Temel, Jonathan Rosand, Joseph A Greer, Ana-Maria Vranceanu

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Neurocritical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kelly M ShafferBehavioral Medicine Service, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, One Bowdoin Square, 7th Floor, Suite 758, Boston, MA, 02114, USA.
Jamie M JacobsBehavioral Medicine Service, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, One Bowdoin Square, 7th Floor, Suite 758, Boston, MA, 02114, USA.
Jessica N ColemanBehavioral Medicine Service, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, One Bowdoin Square, 7th Floor, Suite 758, Boston, MA, 02114, USA.
Jennifer S TemelDepartment of Medicine, Division of Hematology and Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Jonathan RosandDivision of Neurocritical Care and Emergency Neurology, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Joseph A GreerBehavioral Medicine Service, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, One Bowdoin Square, 7th Floor, Suite 758, Boston, MA, 02114, USA.
Ana-Maria VranceanuBehavioral Medicine Service, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, One Bowdoin Square, 7th Floor, Suite 758, Boston, MA, 02114, USA. avranceanu@partners.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Psychosocial Palliative & Community Research in CancerT32CA009461 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI JENNIFER L HAY, Jamie S. Ostroff · 1985 to 2026
$10.1M
Enhancing Scientific Inquiry in Clinical Neurosciences Through Methodology TrainiR25NS088248 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COFFEY, CHRISTOPHER S., GUTMANN, LAURIE · 2014 to 2018
$2.3M
A Randomized trial of early palliative care for newly diagnosed cancer patientsR01NR012735 · NINR · MASSACHUSETTS GENERAL HOSPITAL · PI TEMEL, JENNIFER SUE · 2011 to 2015
$2.1M
Optimizing Palliative and End of Life Care for Patients with CancerK24CA181253 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI TEMEL, JENNIFER SUE · 2014 to 2018
$737k
National Cancer Institute K24 CA181253National Institute of Neurological Disorders and Stroke 5R25NS088248-02National Institute of Nursing Research R01 NR012735NCI NIH HHS K24 CA181253NCI NIH HHS P30 CA008748NCI NIH HHS T32 CA009461NINDS NIH HHS R25 NS088248NINR NIH HHS R01 NR012735
6 · The paper itself

Abstract

backgroundAnxiety and depression are common among patients with acute illness and their families. In oncology, psychosocial services addressing these symptoms are increasingly part of regular practice. Less is known about psychiatric distress among patients with acute neurological injury (ANI) and their family caregivers. To highlight this inequity in psychosocial intervention across medical services, we compared anxiety and depressive symptomatology shortly following diagnosis among patients facing incurable cancer or ANI and their family caregivers.

methodsRecruited from the same hospital, participants were patients within 8 weeks of receiving a diagnosis of incurable cancer (N = 350) and their family caregivers (N = 275; total patient/caregiver dyads = 275) and patients hospitalized in the Neuroscience ICU in the past 2 weeks (N = 81) and their family caregivers (N = 95; total dyads = 75). Participants reported anxiety and depressive symptoms using the Hospital Anxiety and Depression Scale. Symptomatology was compared across illnesses using independent samples t-tests and multiple regressions controlling for differences in sample demographics.

resultsPatients with ANI (M = 6.90) reported greater anxiety symptoms than those with cancer (M = 5.31, p < .001), while caregivers for patients with ANI (M = 5.45) reported greater depressive symptoms than caregivers for patients with cancer (M = 3.81, p < .001). Results remained when controlling for demographic differences between samples.

conclusionThis is the first cross-comparison of psychiatric distress in patients and family caregivers affected by two distinct, life-threatening illnesses early in the illness trajectory. Findings support the priority of addressing psychiatric distress among patients with ANI and their family caregivers, as has been emphasized in the psychosocial oncology field.

Indexed as

AdultAgedAnxietyCaregiversDepressionFamilyFemaleHumansMaleMiddle AgedNeoplasmsPalliative CareTrauma, Nervous SystemAnxietyDepressionFamily caregiverIncurable cancerNeuroscience ICUPsychosocial intervention

Identifiers

PMID28032249
PMCPMC5537031

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.