Evidence map›Paper›PMID 28032184›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2017

Unique effects of energy versus estrogen deficiency on multiple components of bone strength in exercising women.

E A Southmayd, R J Mallinson, N I Williams, D J Mallinson, M J De Souza

Abstract read
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In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.

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  5. Effects of Estrogen Replacement on Bone Geometry and Microarchitecture in Adolescent and Young Adult Oligoamenorrheic Athletes: A Randomized Trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

E A SouthmaydWomen's Health and Exercise Lab, Department of Kinesiology, Pennsylvania State University, University Park, State College, PA, 16802, USA. eas5377@psu.edu.
R J MallinsonWomen's Health and Exercise Lab, Department of Kinesiology, Pennsylvania State University, University Park, State College, PA, 16802, USA.
N I WilliamsWomen's Health and Exercise Lab, Department of Kinesiology, Pennsylvania State University, University Park, State College, PA, 16802, USA.
D J MallinsonSchool of Social and Behavioral Sciences, Stockton University, 101 Vera King Farris Drive, Galloway, NJ, 08205, USA.
M J De SouzaWomen's Health and Exercise Lab, Department of Kinesiology, Pennsylvania State University, University Park, State College, PA, 16802, USA.
Pennsylvania State University · USStockton University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many female athletes are energy and/or estrogen deficient, but the independent effects on bone health have not been isolated. Energy deficiency was detrimental at the tibia while estrogen deficiency was detrimental at the radius. Nutrition must be considered alongside menstrual recovery when addressing compromised bone health in female athletes.

introductionThe purpose of this study was to describe volumetric bone mineral density (vBMD), bone geometry, and estimated bone strength in exercising women (n = 60) grouped according to energy status (energy replete (EnR: n = 30) vs. energy deficient (EnD: n = 30)) and estrogen status (estrogen replete (E

methodsEnergy status was determined using the ratio of measured to predicted resting energy expenditure (mREE/pREE). Estrogen status was based on self-reported menstrual status confirmed by daily evaluation of urinary estrone-1-glucoronide (E1G), pregnanediol glucuronide (PdG), and luteinizing hormone (LH). Eumenorrheic women were considered E

resultsEnD women exhibited lower total vBMD, trabecular vBMD, cortical area, and BSI at the distal tibia and lower total vBMD, smaller cortical area and cortical thickness, and larger endosteal circumference at the proximal tibia compared to EnR women (p < 0.042). E

conclusionsEfforts to correct energy deficiency, which in turn may promote reproductive health, are warranted in order to address the unique contributions of energy status versus estrogen status to bone health.

Indexed as

AdolescentAdultAnthropometryBone DensityCross-Sectional StudiesEnergy MetabolismEstrogensExerciseFemaleHumansMenstrual CycleRadiusTibiaTomography, X-Ray ComputedYoung AdultEstrogensBone geometryEnergy deficiencyEstimated bone strengthFemale athlete triadpQCTVolumetric bone mineral density

Identifiers

PMID28032184
OpenAlexW2561095800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.