Evidence map›Paper›PMID 28032063›Full record

ArticleIranian journal of public health2016

Carcinogen Risk Assessment of Polycyclic Aromatic Hydrocarbons in Drinking Water, Using Probabilistic Approaches.

Hamid Karyab, Masud Yunesian, Simin Nasseri, Noushin Rastkari, Amirhosein Mahvi, Ramin Nabizadeh

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hamid KaryabDept. of Environmental Health Engineering, School of Public Health, Qazvin University of Medical Sciences, Qazvin, Iran; Center for Water Quality Research, Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran.
Masud YunesianDept. of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Simin NasseriDept. of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Noushin RastkariDept. of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Amirhosein MahviDept. of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Ramin NabizadehDept. of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study was focused on the probability of carcinogen risk of low-level ingestion and dermal exposure with polycyclic aromatic hydrocarbons (PAHs) from drinking water in Tehran, capital of Iran.

methodsConcentrations of 16 PAHs were measured in the tap, bottled and heated tap water in four different seasons. Using a questionnaire-based survey, exposure with PAHs from drinking water was evaluated via direct ingestion, swimming, washing and showering. Finally, a comprehensive risk assessment was performed in four age groups. Rank correlation was used to represent variability in risk analysis and obtained coefficients were used for sensitivity analysis. In addition, Monte Carlo simulation was implemented to determine risk probability distributions and to calculate cumulative probability of the total risks in different age groups.

resultsThe lifetime average daily dose and the dermal absorbed dose were 0.69E-06 and 1.33E-05 mg/kg/day, respectively. The total estimated excess lifetime cancer risk (ELCR) of ingestion and dermal exposure were 1.57E-05 and 17.24E-05.

conclusionSum of estimated ingestion and dermal ELCR was 18.81E-05, which was higher than the acceptable value recommended by WHO. It means a total of 1504 lifetime cancer cases in residents of Tehran. Monte Carlo simulation indicated that risk probability above the acceptable level was 96.2% in dermal exposure. Moreover, sensitivity analysis indicated that tap water consumption (P

Indexed as

Drinking waterIranRisk assessmentUncertainties

Identifiers

PMID28032063
PMCPMC5182254
OpenAlexW2558491102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.