Evidence map›Paper›PMID 28032022›Full record

ArticleChemistryOpen2016

Direct Assembly of Prenylated Heteroarenes through a Cascade Minisci Reaction/Dehydration Sequence.

Dong-Hang Tan, Yao-Fu Zeng, Yao Liu, Wen-Xin Lv, Qingjiang Li, Honggen Wang

Abstract read
In one paragraph

Article in ChemistryOpen, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dong-Hang TanSchool of Pharmaceutical Sciences Sun Yat-sen University Guangzhou 510006 P. R. China.
Yao-Fu ZengSchool of Pharmaceutical Sciences Sun Yat-sen University Guangzhou 510006 P. R. China.
Yao LiuSchool of Pharmaceutical Sciences Sun Yat-sen University Guangzhou 510006 P. R. China.
Wen-Xin LvSchool of Pharmaceutical Sciences Sun Yat-sen University Guangzhou 510006 P. R. China.
Qingjiang LiSchool of Pharmaceutical Sciences Sun Yat-sen University Guangzhou 510006 P. R. China.
Honggen WangSchool of Pharmaceutical Sciences Sun Yat-sen University Guangzhou 510006 P. R. China.ORCID 0000-0002-9648-6759

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prenyl group is an important component in bioactive compounds. Herein, we report the assembly of prenylated heteroarenes through a cascade Minisci reaction and acid-promoted dehydration sequence. The use of potassium (3-hydroxy-3-methylbut-1-yl)trifluoroborate as a new coupling reagent allows the direct introduction of prenyl and 3-hydroxy-3-methylbutyl groups to a wide variety of electron-deficient heteroarenes. Synthetic application is also demonstrated.

Indexed as

dehydrationheteroarenesMinisci reactionprenylationradical addition

Identifiers

PMID28032022
PMCPMC5167326

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.