ArticleBrain and behavior2016
Sleep duration and resting fMRI functional connectivity: examination of short sleepers with and without perceived daytime dysfunction.
Article in Brain and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05257317 (Efficacy of Cranial Manual Therapy in the Treatment of Chronic Insomnia Disorder), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Cranial Manual Therapy in the Treatment of Chronic Insomnia Disorder
Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
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- Bayesian estimation of covariate assisted principal regression for brain functional connectivity.Biostatistics (Oxford, England) · 2025Article
- Identification of five sleep-biopsychosocial profiles with specific neural signatures linking sleep variability with health, cognition, and lifestyle factors.PLoS biology · 2025Article
- Thirty minutes of daily artificial gravity does not mitigate head down tilt induced brain activity changes during cognitive task performance.Frontiers in neurology · 2025Article
- A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures.Research square · 2024Article
- Functional brain connectivity predicts sleep duration in youth and adults.Human brain mapping · 2023Article
- Poorer sleep health is associated with altered brain activation during cognitive control processing in healthy adults.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Variability in Resting-State Functional Magnetic Resonance Imaging: The Effect of Body Mass, Blood Pressure, Hematocrit, and Glycated Hemoglobin on Hemodynamic and Neuronal Parameters.Brain connectivity · 2022Article
- Resting-state functional connectivity of the sensory/somatomotor network associated with sleep quality: evidence from 202 young male samples.Brain imaging and behavior · 2022Article
- Chronic Musculoskeletal Pain Moderates the Association between Sleep Quality and Dorsostriatal-Sensorimotor Resting State Functional Connectivity in Community-Dwelling Older Adults.Pain research & management · 2022Article
- The Human Connectome Project: A retrospective.NeuroImage · 2021Review
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- Neuroimaging in Psychiatry and Neurodevelopment: why the emperor has no clothes.The British journal of radiology · 2019Review
- Current Challenges in Translational and Clinical fMRI and Future Directions.Frontiers in psychiatry · 2019Article
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- Differences in self-reported weekend catch up sleep between children and adolescents with and without primary hypertension.Clinical hypertension · 2018Article
- What Can Tweets Tell Us About a Person's Sleep?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2017Article
- Multivariate Heteroscedasticity Models for Functional Brain Connectivity.Frontiers in neuroscience · 2017Article
- Sleep duration and resting fMRI functional connectivity: examination of short sleepers with and without perceived daytime dysfunction.Brain and behavior · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundApproximately 30% of the U.S. population reports recurrent short sleep; however, perceived sleep need varies widely among individuals. Some "habitual short sleepers" routinely sleep 4-6 hr/night without self-reported adverse consequences. Identifying neural mechanisms underlying individual differences in perceived sleep-related dysfunction has important implications for understanding associations between sleep duration and health.
methodThis study utilized data from 839 subjects of the Human Connectome Project to examine resting functional connectivity associations with self-reported short sleep duration, as well as differences between short sleepers with versus without reported dysfunction. Functional connectivity was analyzed using a parcellation covering the cortical, subcortical, and cerebellar gray matter at 5 mm resolution.
resultsSelf-reported sleep duration predicts one of the primary patterns of intersubject variance in resting functional connectivity. Compared to conventional sleepers, both short sleeper subtypes exhibited resting fMRI (R-fMRI) signatures consistent with diminished wakefulness, potentially indicating inaccurate perception of functionality among those denying dysfunction. Short sleepers denying dysfunction exhibited increased connectivity between sensory cortices and bilateral amygdala and hippocampus, suggesting that efficient sleep-related memory consolidation may partly explain individual differences in perceived daytime dysfunction.
conclusionsOverall, current findings indicate that R-fMRI investigations should include assessment of average sleep duration during the prior month. Furthermore, short sleeper subtype findings provide a candidate neural mechanism underlying differences in perceived daytime impairment associated with short sleep duration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.