Evidence map›Paper›PMID 28031967›Full record

ArticleFuture science OA2016

Developmental origin of postnatal cardiomyogenic progenitor cells.

Yuan-Hung Liu, Ling-Ping Lai, Shih-Yun Huang, Yi-Shuan Lin, Shinn-Chih Wu, Chih-Jen Chou, Jiunn-Lee Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future science OA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Every Beat You Take-The Wilms' Tumor Suppressor WT1 and the Heart.International journal of molecular sciences · 2021
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuan-Hung LiuSection of Cardiology, Cardiovascular Center, Far Eastern Memorial Hospital, Pan Chiao, New Taipei City, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taiwan; College of Informatics, Yuan Ze University, Chungli, Taoyuan, Taiwan; Section of Cardiology, Cardiovascular Center, Far Eastern Memorial Hospital, Pan Chiao, New Taipei City, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taiwan; College of Informatics, Yuan Ze University, Chungli, Taoyuan, Taiwan.
Ling-Ping LaiDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Shih-Yun HuangSection of Cardiology, Cardiovascular Center, Far Eastern Memorial Hospital, Pan Chiao, New Taipei City, Taiwan; Section of Cardiology, Cardiovascular Center, Far Eastern Memorial Hospital, Pan Chiao, New Taipei City, Taiwan.
Yi-Shuan LinSection of Cardiology, Cardiovascular Center, Far Eastern Memorial Hospital, Pan Chiao, New Taipei City, Taiwan; Section of Cardiology, Cardiovascular Center, Far Eastern Memorial Hospital, Pan Chiao, New Taipei City, Taiwan.
Shinn-Chih WuDepartment of Animal Science & Technology, National Taiwan University, Taipei, Taiwan; Department of Animal Science & Technology, National Taiwan University, Taipei, Taiwan.
Chih-Jen ChouDepartment of Animal Science & Technology, National Taiwan University, Taipei, Taiwan; Department of Animal Science & Technology, National Taiwan University, Taipei, Taiwan.
Jiunn-Lee LinDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo trace the cell origin of the cells involved in postnatal cardiomyogenesis. MATERIALS &

methodsNkx2.5 enhancer-eGFP (Nkx2.5 enh-eGFP) mice were used to test the cardiomyogenic potential of Nkx2.5 enhancer-expressing cells. By analyzing Cre excision of activated Nkx2.5-eGFP+ cells from different lineage-Cre/Nkx2.5 enh-eGFP/ROSA26 reporter mice, we traced the developmental origin of Nkx2.5 enhancer-expressing cells.

resultsNkx2.5 enhancer-expressing cells could differentiate into striated cardiomyocytes both

conclusionPostnatal Nkx2.5 enhancer-expressing cells are cardiomyogenic progenitor cells and originate from embryonic epicardium-derived cells.

Indexed as

cardiac progenitor cellscardiac regenerationepicardium-derived cellsmyocardial infarctionNkx2.5

Identifiers

PMID28031967
PMCPMC5138010

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.