ReviewFuture science OA2016
The effect of frailty should be considered in the management plan of older people with Type 2 diabetes.
Review in Future science OA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- The current state and development trends of frailty research in diabetic patients: a bibliometric analysis.Frontiers in medicine · 2025Pooled it
- Glycemic levels and cardiovascular events in type 2 diabetes: A cohort study of drugs with different hypoglycemic potentials.Scientific reports · 2025Observational
- Article
- The future of frailty: Opportunity is knocking.Journal of the American Geriatrics Society · 2022Article
- Using an Electronic Health Record and Deficit Accumulation to Pragmatically Identify Candidates for Optimal Prescribing in Patients With Type 2 Diabetes.Diabetes spectrum : a publication of the American Diabetes Association · 2022Article
- Obesity Duration, Severity, and Distribution Trajectories and Cardiovascular Disease Risk in the Atherosclerosis Risk in Communities Study.Journal of the American Heart Association · 2021Article
- Prevalence and factors connected with chronic diseases in the elderly residents of Birjand: a community - based study in Birjand, South Khorasan Province, Iran.Journal of diabetes and metabolic disorders · 2021Article
- Safety and Effectiveness of Ipragliflozin in Elderly Versus Non-elderly Japanese Patients with Type 2 Diabetes: Subgroup Analysis of STELLA-LONG TERM.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021Article
- Evaluating glucose-lowering treatment in older people with diabetes: Lessons from the IMPERIUM trial.Diabetes, obesity & metabolism · 2020Review
- The Association of Frailty with Hospitalizations and Mortality among Community Dwelling Older Adults with Diabetes.The Journal of frailty & aging · 2020Article
- Exposure to hypoglycemia and risk of stroke.Annals of the New York Academy of Sciences · 2018Review
- Loss of skeletal muscle mass and its predictors in type 2 diabetes patients under a multifaceted treatment approach.Diabetology international · 2017Article
- Welcome to volume 3 ofFuture science OA · 2017Article
- Is There an Association Between Metformin Exposure and Frailty?Gerontology & geriatric medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of diabetes is increasing especially in older age due to increased life expectancy. In old age, diabetes is associated with high comorbidity burden and increased prevalence of geriatric syndromes including frailty in addition to micro- and macro-vascular complications. The emergence of frailty may change the natural history of Type 2 diabetes from a progressive to a regressive course with increased risk of hypoglycemia. This may result in normalization of blood glucose levels and lead to a state of burnt-out diabetes in frail older people with significant weight loss. Although guidelines suggest relaxed glycemic control in frail elderly with diabetes, complete withdrawal of hypoglycemic medications may be necessary in these frail populations to reduce the risk of hypoglycemia.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.