Evidence map›Paper›PMID 28031913›Full record

ReviewFuture science OA2015

Lymphatic network in atherosclerosis: the underestimated path.

Andreea Milasan, Jonathan Ledoux, Catherine Martel

Open access · goldAbstract readReview
In one paragraph

Review in Future science OA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Regulation of Lymphatic Function in Obesity.Frontiers in physiology · 2020
    Review
  11. Lymphatic Function and Dysfunction in the Context of Sex Differences.ACS pharmacology & translational science · 2019
    Review
  12. HDL and Reverse Cholesterol Transport.Circulation research · 2019
    Review
  13. Review
  14. Review
  15. The Intestinal Lymphatic System: Functions and Metabolic Implications.Cellular and molecular gastroenterology and hepatology · 2019
    Review
  16. Article
  17. Article
  18. Cardiac Lymphatics: An Example of Systems Biology in Medicine.Integrative medicine (Encinitas, Calif.) · 2017
    Article
  19. Article
  20. Welcome to volume 2 ofFuture science OA · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Andreea MilasanMontreal Heart Institute, Research Center, Montreal, QC, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada; Montreal Heart Institute, Research Center, Montreal, QC, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Jonathan LedouxMontreal Heart Institute, Research Center, Montreal, QC, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada; Montreal Heart Institute, Research Center, Montreal, QC, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Catherine MartelMontreal Heart Institute, Research Center, Montreal, QC, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada; Montreal Heart Institute, Research Center, Montreal, QC, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Montreal Heart Institute · CAUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lymphatic system is a key component of tissue fluid homeostasis. In contrast to the closed and high-pressure blood vascular system, the lymphatic vascular system transports lymph in an open and low-pressure network. A prerequisite player in the transport of immune cells and cholesterol metabolism, it has been understudied until recently. Whereas defects in lymph circulation are mostly associated with pathologies such as congenital or acquired lymphedema, emerging significant developments are unraveling the role of lymphatic vessels in other pathological settings. In the last decade, discoveries of underlying genes responsible for developmental and postnatal lymphatic growth, combined with state-of-the-art lymphatic function imaging and quantification techniques, have matched the growing interest in understanding the role of the lymphatic system in atherosclerosis. With a historical perspective, this review highlights the current knowledge regarding interaction between the lymphatic vascular tree and atherosclerosis, with an emphasis on the physiological mechanisms of this multifaceted system throughout disease onset and progression.

Indexed as

atherosclerosislymphatic endotheliumlymphatic smooth muscle cellslymphatic vessels

Identifiers

PMID28031913
PMCPMC5138008
OpenAlexW2175999675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.