ArticleThe World Allergy Organization journal2016
Fatal asthma; is it still an epidemic?
Article in The World Allergy Organization journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 40 citations in OpenAlex.
- Analysing allergen-environment interactions to identify drivers of asthma presentations in Metropolitan Melbourne, 2017-2022.Scientific reports · 2026Article
- Evaluation of the Relationship Between Air Pollutants and Emergency Department Admissions with Childhood Asthma.Diagnostics (Basel, Switzerland) · 2024Article
- Asthma severity: the patient's point of view.European clinical respiratory journal · 2024Article
- Relative Humidity and Its Impact on the Immune System and Infections.International journal of molecular sciences · 2023Review
- Impact of Fungal Spores on Asthma Prevalence and Hospitalization.International journal of molecular sciences · 2022Review
- Biologics and global burden of asthma: A worldwide portrait and a call for action.The World Allergy Organization journal · 2021Article
- The potential role of local pharmacies to assess asthma control: an Italian cross-sectional study.BMC public health · 2021Article
- Uncontrolled Asthma: Unmet Needs in the Management of Patients.Journal of asthma and allergy · 2021Review
- The allergenic activity and clinical impact of individual IgE-antibody binding molecules from indoor allergen sources.The World Allergy Organization journal · 2020Review
- Aberrant MicroRNAomics in Pulmonary Complications: Implications in Lung Health and Diseases.Molecular therapy. Nucleic acids · 2019Review
- Establishment and characterization of a multi-purpose large animal exposure chamber for investigating health effects.The Review of scientific instruments · 2019Article
- Trends and determinants of Emergency Room admissions for asthma: A retrospective evaluation in Northeast Italy.The World Allergy Organization journal · 2019Article
- Extracorporeal membrane oxygenation for life-threatening asthma refractory to mechanical ventilation: analysis of the Extracorporeal Life Support Organization registry.Critical care (London, England) · 2017Article
- Role of Type 2 Innate Lymphoid Cells in Allergic Diseases.Current allergy and asthma reports · 2017Review
- Zero tolerance for asthma deaths in children.Jornal de pediatriaArticle
- Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsthma mortality has declined since the 1980s. Nevertheless the World Health Organization (WHO) identified asthma as responsible for 225.000 deaths worldwide in 2005, and 430.000 fatal cases are expected by 2030. Some unexpected and concentrated fatal asthma events all occurred between 2013 and 2015 in Veneto, a North Eastern region of Italy, which prompted a more in-depth investigation of characteristics and risk factors.
methodsA web search including key words related to fatal asthma in Italy between 2013 and 2015 has been performed. Concerning the cases that occurred in Veneto, subjects' clinical records have been evaluated and details about concomitant weather conditions, pollutants and pollen count have been collected.
resultsTwenty-three cases of asthma deaths were found in Italy; 16 of them (69%) occurred in the Veneto Region. A prevalence of male and young age was observed. Most of patients were atopic, died in the night-time hours and during the weekends. The possible risk factors identified were the sensitization to DISCUSSION: Although not free from potential biases, our web search and further investigations highlight an increasing asthma mortality trend, similarly to what other observatories report. The analysis of available clinical data suggests that the lack of treatment more than a severe asthma phenotype characterizes the fatal events.
conclusionsAsthma mortality still represents a critical issue in the management of the disease, particularly in youngsters. Once more the inadequate treatment and the lack of adherence seem to be not only related to the uncontrolled asthma but also to asthma mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.